D5919
Diacylglycerol Kinase Inhibitor I
solid
Synonym(s):
6-[2-[4-[(4-Fluorophenyl)phenylmethylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo-[3,2-a]-pyrimidin-5-one, R59022
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
1 mg | Check Cart for Availability | $141.00 $119.85 |
5 mg | Check Cart for Availability | $485.00 $412.25 |
About This Item
$119.85
List Price$141.00Save 15%biological source
synthetic (organic)
Quality Segment
assay
≥98% (HPLC)
form
solid
color
pale yellow
solubility
0.1 M HCl: slightly soluble, 0.1 M NaOH: slightly soluble, DMSO: soluble, H2O: insoluble, ethanol: soluble, ethyl acetate: soluble
storage temp.
−20°C
SMILES string
CC1=C(CCN2CCC(\CC2)=C(\c3ccccc3)c4ccc(F)cc4)C(=O)N5C=CSC5=N1
InChI
1S/C27H26FN3OS/c1-19-24(26(32)31-17-18-33-27(31)29-19)13-16-30-14-11-22(12-15-30)25(20-5-3-2-4-6-20)21-7-9-23(28)10-8-21/h2-10,17-18H,11-16H2,1H3
InChI key
MFVJXLPANKSLLD-UHFFFAOYSA-N
General description
Application
Biochem/physiol Actions
1 of 1
This Item | |||
|---|---|---|---|
| description solid | description solid | description The Rho kinase inhibitor, CAS 872543-07-6, is a cell-permeable, highly specific, reversible, potent, and ATP-competitive inhibitor of Rho-associated kinase (ROCK; Ki = 1.6 nM). | description The Sphingosine Kinase Inhibitor, also referenced under CAS 1177741-83-1, controls the biological activity of Sphingosine Kinase. This small molecule/inhibitor is primarily used for Cell Signaling applications. |
| form solid | form solid | form solid | form solid |
| assay ≥98% (HPLC) | assay ≥97% (HPLC) | assay ≥95% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility 0.1 M NaOH: slightly soluble, ethyl acetate: soluble, H2O: insoluble, DMSO: soluble, 0.1 M HCl: slightly soluble, ethanol: soluble | solubility H2O: insoluble, DMSO: soluble, 0.1 M NaOH: slightly soluble, ethyl acetate: soluble, ethanol: soluble, 0.1 M HCl: slightly soluble | solubility water: 5 mg/mL, methanol: 5 mg/mL | solubility DMSO: 5 mg/mL |
| color pale yellow | color pale yellow | color white | color white |
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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