D7628
Dihydrouracil
powder
Synonym(s):
5,6-Dihydro-2,4-dihydroxypyrimidine
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 g | Check Cart for Availability | $172.00 |
About This Item
Empirical Formula (Hill Notation):
C4H6N2O2
CAS Number:
Molecular Weight:
114.10
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352005
EC Number:
207-982-1
MDL number:
Form:
powder
form
powder
mp
279-281 °C (lit.)
SMILES string
O=C1CCNC(=O)N1
InChI
1S/C4H6N2O2/c7-3-1-2-5-4(8)6-3/h1-2H2,(H2,5,6,7,8)
InChI key
OIVLITBTBDPEFK-UHFFFAOYSA-N
General description
Dihydrouracil (DiHU) is a minor base found in transfer ribonucleic acid (tRNA). It is similar to uracil with the only exception that the C5-C6 bond is saturated. It crystallized in the monoclinic system with space group P21/C. Its crystalline structure has been analyzed. Its generation from L-cysteine and uracil via photochemical addition has been described.
Application
Dihydrouracil has been used as a standard for ureido group in the colorimentric assay of transfer ribonucleic acid (tRNA).[1]
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This Item | |||
|---|---|---|---|
| Quality Level 100 | Quality Level 300 | Quality Level 200 | Quality Level 200 |
| form powder | form powder | form powder | form - |
| mp 279-281 °C (lit.) | mp >300 °C (lit.) | mp >300 °C (lit.) | mp 197-200 °C (lit.) |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Articles
A shortened review of fundamentals of Porous Graphitic Carbon (PGC) materials. What they are and how do they work as a stationary phase material in HPLC?.
Sylke Schneider et al.
Journal of the American College of Surgeons, 200(3), 336-344 (2005-03-02)
To find out if neoadjuvant therapy could alter tumor response determinants that might affect tumor sensitivity to the treatment, we investigated intratumoral expressions of genes associated with chemosensitivity, radiosensitivity, or both before and after radiochemotherapy. Twenty-four patients with locally advanced
Cuiping Liu et al.
Methods in enzymology, 469, 69-93 (2009-01-01)
Transfer RNA (tRNA) molecules mediate translation of the nucleic acid genetic code into the amino acid building blocks of proteins, thus ensuring the survivability of cells. The dynamic properties of tRNA molecules are crucial to their functions in both activity
Futao Yu et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(49), 19593-19598 (2011-11-30)
Dihydrouridine (D) is a highly conserved modified base found in tRNAs from all domains of life. Dihydrouridine synthase (Dus) catalyzes the D formation of tRNA through reduction of uracil base with flavin mononucleotide (FMN) as a cofactor. Here, we report
Global Trade Item Number
| SKU | GTIN |
|---|---|
| D7628-5G | 04061833588611 |