This product does not absorb strongly in the visible spectrum. The extinction coefficient has not been measured. Note that Resorufin sodium salt has a molar extinction coefficient of 73,000 in 0.1 M Tris-HCl buffer, pH 8.0, containing 0.1 M NaCl. This value is likely quite similar to that of the hydrolysis product of D7816, which would be 6-Methylresorufin sodium salt.
D7816
1,2-Di-O-lauryl-rac-glycero-3-glutaric acid 6′-methylresorufin ester
lipase substrate, solid
Synonym(s):
Chromogenic lipase substrate
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 mg | Check Cart for Availability | $636.00 |
About This Item
$636.00
Check Cart for Availability
Product Name
1,2-Di-O-lauryl-rac-glycero-3-glutaric acid 6′-methylresorufin ester, lipase substrate
Quality Level
form
solid
storage temp.
2-8°C
SMILES string
CCCCCCCCCCCCOCC(COC(=O)CCCC(=O)Oc1ccc2N=C3C=CC(=O)C=C3Oc2c1C)OCCCCCCCCCCCC
InChI
1S/C45H69NO8/c1-4-6-8-10-12-14-16-18-20-22-31-50-34-38(51-32-23-21-19-17-15-13-11-9-7-5-2)35-52-43(48)25-24-26-44(49)53-41-30-29-40-45(36(41)3)54-42-33-37(47)27-28-39(42)46-40/h27-30,33,38H,4-26,31-32,34-35H2,1-3H3
InChI key
JEGLJLCZRAWOBI-UHFFFAOYSA-N
Application
Chromogenic substrate for lipase
Biochem/physiol Actions
1,2-Di-O-lauryl-rac-glycero-3-glutaric acid 6′-methylresorufin ester (DGGR) is more pancreas-specific. Hence the DGGR lipase assay may be preferred as a substitute to spec cPL in diagnostic cases with suspected pancreatitis.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Narmadaa Thyagarajan et al.
Lipids, 52(3), 189-205 (2017-02-17)
Macrophage lipoprotein lipase (LPL) induces lipid accumulation and promotes atherosclerosis. However, the effects of lipoprotein hydrolysis products generated by LPL on macrophage-derived foam cell formation are not clearly understood. Thus, we analyzed the transcriptomic response to hydrolysis products via microarray
Validation of a commercial 1, 2-o-dilauryl-rac-glycero glutaric acid-(6?-methylresorufin) ester lipase assay for diagnosis of canine pancreatitis
Goodband E L, et al.
Veterinary record open, 5(1), e000270-e000270 (2018)
Breanne M Coady et al.
Journal of peptide science : an official publication of the European Peptide Society, 24(11), e3123-e3123 (2018-10-06)
Human hepatic lipase (hHL) is a cell surface associated enzyme that hydrolyzes triacylglycerols and phospholipids within circulating lipoproteins. We hypothesized that an amino acid sequence mimicking the major heparin binding domain (HBD) of hHL will displace hHL from cell surfaces.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| D7816-10MG | 04061832923840 |
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Do you have informatoin on the molar extinction coefficient of 1,2-Di-O-lauryl-rac-glycero-3-glutaric acid 6′-methylresorufin ester? Thanks
1 answer-
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