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E0761

Ebelactone A microbial

esterase inhibitor

Synonym(s):

3,11-Dihydroxy-2,4,6,8,10,12-hexamethyl-9-oxo-6-tetradecenoic acid 1,3-lactone

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1 MG

$429.00

$429.00

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About This Item

Empirical Formula (Hill Notation):
C20H34O4
CAS Number:
76808-16-7
Molecular Weight:
338.48
NACRES:
NA.77
PubChem Substance ID:
24894373
UNSPSC Code:
12352202
MDL number:
MFCD00036710

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form

powder

InChI

1S/C20H34O4/c1-8-12(3)17(21)15(6)18(22)13(4)9-11(2)10-14(5)19-16(7)20(23)24-19/h9,12-17,19,21H,8,10H2,1-7H3/b11-9+/t12-,13-,14+,15+,16+,17-,19+/m1/s1

SMILES string

[H][C@@]1([C@H](C/C(C)=C/[C@H](C([C@H]([C@@H]([C@@H](CC)C)O)C)=O)C)C)OC([C@H]1C)=O

InChI key

WOISDAHQBUYEAF-QIQXJRRPSA-N

biological source

Streptomyces sp.

assay

≥98% (HPLC)

solubility

methanol: 10 mg/mL, clear, colorless

storage temp.

2-8°C

Quality Level

100

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This Item
B6542B5936N7779
Ebelactone A microbial esterase inhibitor

Sigma-Aldrich

E0761

Ebelactone A microbial

Brefeldin A ≥99% (HPLC and TLC), BioXtra, Molecular Biology

Sigma-Aldrich

B6542

Brefeldin A

Brefeldin A Ready Made Solution, from Penicillium brefeldianum, 10 mg/mL in DMSO

Sigma-Aldrich

B5936

Brefeldin A

Nojirimycin bisulfite microbial solid

Sigma-Aldrich

N7779

Nojirimycin bisulfite microbial

assay

≥98% (HPLC)

assay

≥99% (HPLC and TLC)

assay

-

assay

≥98% (TLC)

biological source

Streptomyces sp.

biological source

Penicillium brefeldianum

biological source

Penicillium brefeldianum

biological source

Streptomyces sp.

Quality Level

100

Quality Level

300

Quality Level

200

Quality Level

100

form

powder

form

powder

form

solution

form

solid

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

solubility

methanol: 10 mg/mL, clear, colorless

solubility

DMSO: 10 mg/mL (Store stock solutions at -20 °C)

solubility

DMSO: 10 mg/mL

solubility

-

General description

Esterase inhibitors produced by Streptomyces sp. MG7-G1 strain

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX7876
MKCP5578
MKCL2829
MKCJ1250
MKCH0498

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S Banerjee et al.
Cancer research, 51(4), 1092-1098 (1991-02-15)
Levels of estradiol 17 beta-ester hydrolytic activity in the breast cyst fluid (BCF) from 25 different women with fibrocystic disease of the breast were found to vary over a wide range (0-2.4 nmol/min/mg protein for estradiol acetate). On the basis
I A Hoskins et al.
American journal of obstetrics and gynecology, 163(6 Pt 1), 1944-1947 (1990-12-01)
Assessment of leukocyte esterase activity in amniotic fluid for the rapid and reliable diagnosis of chorioamnionitis has been demonstrated previously. We compared in vitro inhibition of esterase activity in amniotic fluid with bacterial cultures to identify the origins of the
Gianfranco De Pascale et al.
The Journal of antibiotics, 64(7), 483-487 (2011-04-28)
Homoserine transacetylase (HTA) catalyzes the transfer of an acetyl group from acetyl-CoA to the hydroxyl group of homoserine. This is the first committed step in the biosynthesis of methionine (Met) from aspartic acid in many fungi, Gram-positive and some Gram-negative
Amit K Mandal
Organic letters, 4(12), 2043-2045 (2002-06-07)
[structure: see text] The highly stereocontrolled hydroboration of an alkene, a subsequent Suzuki-Miyaura cross-coupling reaction, a silylcupration on a nonterminal acetylene, and an iododesilylation were the key steps in a convergent total synthesis of (-)-ebelactone A.
Low-molecular-weight immunomodifiers produced by micro-organisms.
H Umezawa
Biotechnology & genetic engineering reviews, 3, 255-273 (1985-01-01)
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