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Epidermal Growth Factor from murine submaxillary gland

Name: Epidermal Growth Factor from murine submaxillary gland
Brand: SIGMA
Price: 452 USD
Availability: InStock

lyophilized powder, BioReagent, suitable for cell culture

Synonym(s):

EGF, Epidermal cell growth factor

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Size/SKU	Availability	Price
0.1 mg	Estimated to ship onNovember 25, 2026fromMILWAUKEE	$452.00

About This Item

CAS Number:

62229-50-9

UNSPSC Code:

12352202

EC Number:

263-468-7

NACRES:

NA.32

MDL number:

MFCD01634807

$452.00

Estimated to ship onNovember 25, 2026Details

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Properties

biological source

mouse submaxillary glands

Quality Segment

200

product line

BioReagent

assay

≥98% (SDS-PAGE)

form

lyophilized powder

potency

0.02-2.0 ng/mL EC₅₀

packaging

pkg of 0.1 mg

storage condition

avoid repeated freeze/thaw cycles

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white

UniProt accession no.

P01132

storage temp.

2-8°C

Gene Information

mouse ... Egf(13645)

Description

General description

Epidermal growth factor (EGF) is the member of EGF-like family of growth factors, that binds to EGF receptor. It is majorly expressed in kidney, parotid gland and salivary gland.

Application

Epidermal Growth Factor from murine submaxillary gland has been used

in studying its effects on the development of caustic esophageal stricture in rats
for preparation of MCF-10A cell line
for the culture of primary hair follicle stem cells from arbas cashmere goat (gHFSCs) and adhesion of hair follicles (HF)

Biochem/physiol Actions

Epidermal growth factor (EGF) blocks gastric acid and pepsin secretion and increases gastrointestinal cell proliferation. EGF stimulates proliferation and migration in bone marrow stromal cells (BMSC), that gives rise to osteoblasts, chondrocytes and adipocytes. It functions as a strong mitogenic factor for various cultured cells. Mutations in this gene is linked to hypomagnesemia. EGF plays a major role in the maintenance of hair and skin development.

Physical form

Lyophilized from 0.2 μm filtered solution in ammonium acetate buffer.

Preparation Note

Purified by gel filtration and ion-exchange chromatography.

Analysis Note

The biological activity is measured in a proliferation assay using BALB/MK cells.

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This Item	E4127	E5160	N0513
Sigma-Aldrich E1257 Epidermal Growth Factor from murine submaxillary gland	Sigma-Aldrich E4127 Epidermal Growth Factor from murine submaxillary gland	Sigma-Aldrich E5160 Epidermal Growth Factor from mouse	Sigma-Aldrich N0513 Nerve Growth Factor-7S from murine submaxillary gland
description lyophilized powder, BioReagent, suitable for cell culture	description EGF, suitable for cell culture	description EGF	description NGF-7S, lyophilized powder, suitable for cell culture
biological source mouse submaxillary glands	biological source mouse submaxillary glands	biological source mouse	biological source mouse
assay ≥98% (SDS-PAGE)	assay -	assay ≥90% (SDS-PAGE)	assay -
technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
form lyophilized powder	form lyophilized powder	form lyophilized powder	form lyophilized powder
impurities endotoxin, tested	impurities ≤50 EU/vial (LAL test)	impurities ≤1 EU/μg endotoxin (Protein)	impurities ≤10

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Storage Class

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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