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E1406

Embelin

≥98% (HPLC), powder

Sinónimos:

2,5-Dihydroxy-3-undecyl-2,5-cyclohexadiene-1,4-dione, Embelic acid, Emberine

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A ustedes/SKUDisponibilidadPrecio
10 mg
Comprobar disponibilidad del carrito
US$ 150,00
50 mg
Comprobar disponibilidad del carrito
US$ 542,00

Acerca de este artículo

Fórmula empírica (notación de Hill):
C17H26O4
Número CAS:
Peso molecular:
294.39
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
208-979-8
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

US$ 150,00

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Quality Segment

assay

≥98% (HPLC)

form

powder

solubility

DMSO: >10 mg/mL, H2O: insoluble

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria, parasites

mode of action

DNA synthesis | interferes

SMILES string

CCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O

InChI

1S/C17H26O4/c1-2-3-4-5-6-7-8-9-10-11-13-16(20)14(18)12-15(19)17(13)21/h12,18,21H,2-11H2,1H3

InChI key

IRSFLDGTOHBADP-UHFFFAOYSA-N

Gene Information

human ... XIAP(331)

General description

Embelin, a natural benzoquinone-derivative, was initially extracted from Embelia ribes plant.[1] It is structurally similar to ubiquinone.[2]

Application

Embelin has been used:
  • to study its effects on the receptor activator of nuclear factor kappa-B ligand (RANKL)-induced nuclear factor of activated T cells (NFATc1) luciferase activity[3]
  • to study its role in the mechanisms mediating Parkinson′s disease (PD)[2]
  • in treating whole mouse embryos to determine its effects on the X-linked inhibitory apoptosis protein (XIAP) activity[1]

Biochem/physiol Actions

Embelin is an inhibitor of XIAP (X-linked inhibitor-of-apoptosis protein); in vivo antitumor and anti-inflammatory activity.
Embelin elicits anti-oxidant, mitochondrial uncoupling, and anti-fertility properties.[2][4] It also has anti-diabetic, anti-convulsant, anxiolytic, and anti-microbial activities.[4] Embelin acts as a potent neuroprotective agent and is also beneficial as an adjunct therapy for cerebral stroke.

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1 of 1

Este artículo
178493PHL89654I5659
Embelin phyproof® Reference Substance

PHL89654

Embelin

assay

≥98% (HPLC)

assay

-

assay

≥90.0% (HPLC)

assay

≥98% (HPLC)

form

powder

form

solid

form

-

form

powder

solubility

DMSO: >10 mg/mL, H2O: insoluble

solubility

DMSO: 10 mg/mL, methanol: 5 mg/mL

solubility

-

solubility

methanol: 50 mg/mL, clear to slightly hazy

Gene Information

human ... XIAP(331)

Gene Information

-

Gene Information

-

Gene Information

-

antibiotic activity spectrum

Gram-negative bacteria, parasites, Gram-positive bacteria

antibiotic activity spectrum

-

antibiotic activity spectrum

-

antibiotic activity spectrum

-

mode of action

DNA synthesis | interferes

mode of action

-

mode of action

-

mode of action

-


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pictograms

Health hazard

signalword

Warning

hcodes

Hazard Classifications

Repr. 2

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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