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E4644

Anti-Erythropoietin Receptor antibody produced in goat

affinity isolated antibody

Synonym(s):

Anti-EPO R, Anti-EPO Receptor

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Pack SizeSKUAvailabilityPrice
0.1 mg

Available to ship TODAYfromMILWAUKEE

$628.00
$533.80

About This Item

UNSPSC Code:
51111800
PubChem Substance ID:
24894570
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
8

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biological source

goat

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

technique(s)

western blot: 1 μg/mL

UniProt accession no.

P19235

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... EPOR(2057)

General description

Erythropoietin Receptor (EPO R) is a protein that belongs to type I cytokine receptor superfamily and is expressed mainly in megakaryocytes, erythoid progenitors, endothelial cells and neurons. Erythropoietin binds to EPO receptor and stimulates Jak2 tyrosine kinase which in turn phosphorylate tyrosine residue of EPO receptor and results in activation of several intracellular pathways (Ras/MAP kinase, phosphatidylinositol 3-kinase, and STAT transcription factors). Anti-Erythropoietin Receptor antibody can be used for analyzing the neurite outgrowth. Goat anti-Erythropoietin Receptor antibody reacts specifically with recombinant human erythropoietin receptor.

Immunogen

recombinant human erythropoietin soluble receptor, expressed in NSO cells.

Application

Anti-Erythropoietin Receptor can be used in western blotting at a working antibody concentration of 1 μg/ml for detecting human EPO receptor.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper)

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5% trehalose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Anti-Erythropoietin Receptor antibody produced in goat affinity isolated antibody

Sigma-Aldrich

E4644

Anti-Erythropoietin Receptor antibody produced in goat

Anti-EPO-R antibody produced in rabbit affinity isolated antibody

Sigma-Aldrich

SAB4500780

Anti-EPO-R antibody produced in rabbit

Anti-EPO-R Antibody, clone VP-2E8 clone VP-2E8, from mouse

Sigma-Aldrich

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Anti-EPO-R Antibody, clone VP-2E8

Anti-Erythropoietin antibody produced in rabbit IgG fraction of antiserum, lyophilized powder

Sigma-Aldrich

E2531

Anti-Erythropoietin antibody produced in rabbit

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

biological source

goat

biological source

rabbit

biological source

mouse

biological source

rabbit

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

antibody form

IgG fraction of antiserum

Gene Information

human ... EPOR(2057)

Gene Information

human ... EPOR(2057)

Gene Information

human ... EPOR(2057)

Gene Information

human ... EPO(2056)

clone

polyclonal

clone

polyclonal

clone

VP-2E8, monoclonal

clone

polyclonal

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Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCH9283
MKCH0183
MKBR2971V
MKBQ5768V
091M1482

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Related Content

Data Sheet - E4644

Instructions

Structure, function, and activation of the erythropoietin receptor.
H Youssoufian et al.
Blood, 81(9), 2223-2236 (1993-05-01)
The erythropoietin receptor and the molecular basis of signal transduction.
D L Barber et al.
Seminars in hematology, 29(4), 293-304 (1992-10-01)
María José Vázquez-Mellado et al.
Oncology reports, 41(2), 1333-1341 (2018-11-30)
Erythropoietin (Epo) is used for the treatment of cancer‑associated anaemia. However, certain studies have identified that the administration of Epo mediates the acquisition of resistance to cisplatin, which is widely used to treat cervical cancer. Our group previously reported that
View All Related Papers

Global Trade Item Number

SKUGTIN
E4644-.1MG04061832714141

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