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Anti-LPA₁, C-Terminal antibody produced in rabbit

Name: Anti-LPA<SUB>1</SUB>, C-Terminal antibody produced in rabbit
Brand: SIGMA

IgG fraction of antiserum, buffered aqueous solution

Synonym(s):

Anti-EDG-2, Anti-Endothelial Cell Differentiation Gene 2

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD02686119

Conjugate:

unconjugated

Clone:

polyclonal

Application:

Citations:

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Properties

biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~50 kDa

species reactivity

human, rat

technique(s)

western blot: suitable

UniProt accession no.

Q92633

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... LPAR1(1902)
rat ... Lpar1(116744)

Description

Immunogen

synthetic peptide corresponding to amino acids 328-344 of human EDG-2/LPA₁.

Application

Anti-LPA₁, C-Terminal antibody produced in rabbit is suitable for western blotting at a working dilution of 1:1000 using rat brain microsomal fraction.

Biochem/physiol Actions

Lysophosphatidic acid receptor 1 (LPA1) is a protein encoded by the LPAR1 gene in humans. It is constitutively localized in the nucleus of mammalian cells and may be involved in regulating intranuclear protein phosphorylation and signalling. LPA1 is differentially expressed in androgen-insensitive and LPA-responsive cells. It is not expressed in androgen-dependent and LPA-resistant cells.Its expression is significantly higher in the cancer compared with the benign tissues and may possibly act as a drug target to interfere with progression of prostate cancer. LPA1 helps in promoting cell proliferation, survival and migration by acting on cognate G protein-coupled receptors.

Physical form

Solution in PBS with 0.08% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	SAB1401121	SAB4501004	SAB4503572
$Anti-LPA1, C-Terminal antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution$ Sigma-Aldrich E5017 Anti-LPA₁, C-Terminal antibody produced in rabbit	Sigma-Aldrich SAB1401121 Monoclonal Anti-LPAR1 antibody produced in mouse	Sigma-Aldrich SAB4501004 Anti-EDG7 antibody produced in rabbit	Sigma-Aldrich SAB4503572 Anti-EDG4 antibody produced in rabbit
description IgG fraction of antiserum, buffered aqueous solution	description clone 2E2, purified immunoglobulin, buffered aqueous solution	description affinity isolated antibody	description affinity isolated antibody
biological source rabbit	biological source mouse	biological source rabbit	biological source rabbit
Quality Level 200	Quality Level 100	Quality Level 100	Quality Level 100
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form IgG fraction of antiserum	antibody form purified immunoglobulin	antibody form affinity isolated antibody	antibody form affinity isolated antibody
species reactivity human, rat	species reactivity human	species reactivity rat, mouse, human	species reactivity human
UniProt accession no. Q92633	UniProt accession no. Q92633	UniProt accession no. Q9UBY5	UniProt accession no. Q9HBW0

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10 - Combustible liquids

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Anti-LPA₁, C-Terminal antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Select a Size

About This Item

biological source

Quality Segment

conjugate

antibody form

antibody product type

clone

form

mol wt

species reactivity

technique(s)

UniProt accession no.

shipped in

storage temp.

target post-translational modification

Gene Information

Immunogen

Application

Biochem/physiol Actions

Physical form

Disclaimer

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This Item

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Anti-LPA1, C-Terminal antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Select a Size

About This Item

biological source

Quality Segment

conjugate

antibody form

antibody product type

clone

form

mol wt

species reactivity

technique(s)

UniProt accession no.

shipped in

storage temp.

target post-translational modification

Gene Information

Immunogen

Application

Biochem/physiol Actions

Physical form

Disclaimer

Compare Similar Items

This Item

Still not finding the right product?

Safety Information

Storage Class

Documentation

Certificates of Analysis (COA)

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Anti-LPA₁, C-Terminal antibody produced in rabbit