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F0881

Fusidic acid sodium salt

≥98% (TLC), Bacterial protein synthesis inhibitor

Synonym(s):

Fucidin

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Size/SKUAvailabilityPrice
1 g
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$308.00
5 g
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$1,200.00

About This Item

Linear Formula:
C31H47O6Na
CAS Number:
Molecular Weight:
538.69
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
212-030-3
MDL number:
Assay:
≥98% (TLC)

$308.00


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Product Name

Fusidic acid sodium salt, ≥98% (TLC)

Quality Segment

assay

≥98% (TLC)

solubility

H2O: soluble

antibiotic activity spectrum

neoplastics

mode of action

protein synthesis | interferes

storage temp.

2-8°C

SMILES string

[Na+].C[C@@H]1[C@H](O)CC[C@@]2(C)C1CC[C@@]3(C)C2[C@H](O)CC4\C([C@H](C[C@]34C)OC(C)=O)=C(/CC\C=C(\C)C)C([O-])=O

InChI

1S/C31H48O6.Na/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32;/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36);/q;+1/p-1/b26-20-;/t18-,21-,22-,23+,24+,25-,27-,29-,30-,31-;/m0./s1

InChI key

HJHVQCXHVMGZNC-JCJNLNMISA-M

General description

Fusidic acid is an antibiotic substance, resembling the structure of a steroid. It belongs to the class of fusidanes.

Application

Fusidic acid sodium salt has been used to study the effects of three-drug combinations on the growth rate of a bacterium, wild-type Escherichia coli. It is also used to study the in vitro susceptibility of dog-derived European methicillin-resistant Staphylococcus pseudintermedius and Staphylococcus aureus strains and their methicillin-susceptible counterparts.

Biochem/physiol Actions

Suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA.
Suppresses nitric oxide lysis of pancreatic islet cells; inhibits protein synthesis in prokaryotes.
Fusidic acid possesses antimicrobial action against skin pathogens. It is highly specific to Staphylococcus aureus. It is therefore used for treating infected traumatic wounds, folliculitis, furunculosis, impetigo, erythrasma and abscesses.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

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This Item
Y000141055952N7143
description

≥98% (TLC)

description

European Pharmacopoeia (EP) Reference Standard

description

derivatization grade (HPLC), ≥99.0% (HPLC)

description

≥98% (TLC)

assay

≥98% (TLC)

assay

-

assay

≥99.0% (HPLC)

assay

≥98% (TLC)

Quality Level

200

Quality Level

-

Quality Level

100

Quality Level

300

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

solubility

H2O: soluble

solubility

-

solubility

-

solubility

-

mode of action

protein synthesis | interferes

mode of action

-

mode of action

-

mode of action

cell membrane | interferes

antibiotic activity spectrum

neoplastics

antibiotic activity spectrum

-

antibiotic activity spectrum

-

antibiotic activity spectrum

Gram-positive bacteria


Hazard Classifications

Acute Tox. 4 Oral

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Precautionary Statements

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves



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