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F2177

Follistatin 288 from mouse

>95% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder

Synonym(s):

FS-288

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25 μg
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$940.00
$799.00

About This Item

UNSPSC Code:
51111800
NACRES:
NA.32
MDL number:

$799.00

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biological source

mouse

Quality Segment

recombinant

expressed in baculovirus infected Sf21 cells

assay

>95% (SDS-PAGE)

form

lyophilized powder

potency

0.04-0.4 mg per mL

mol wt

calculated mol wt ~31 kDa

packaging

pkg of 25 μg

storage condition

avoid repeated freeze/thaw cycles

impurities

endotoxin, tested

UniProt accession no.

storage temp.

−20°C

Gene Information

mouse ... Fst(14313)

General description

FST (follistatin) is an activin-binding protein, and exists in two isoforms due to alternate splicing, FS288 and FS315. It is a glycoprotein with a single chain, and acts as an activin antagonist. It has a high level of expression in fetal membranes and placenta.[1][2][3]

Biochem/physiol Actions

FST (follistatin) binds to and regulates activins, which in turn are TGF (transforming growth factor)-β superfamily members. The expression level of FST and its binding partner activin A is elevated in inflammatory disorders.[1] The activin A-follistatin system plays an essential role in the modulation of glucose and lipid metabolism, which might have an overall effect on fetal growth. In adipose tissue, it facilitates the adipogenic differentiation of progenitor cells.[3]
High affinity activin-binding protein that can act as an activin antagonist.

Physical form

Recombinant Mouse Follistatin 288 is supplied as a approximately 25 μg of protein lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% TFA containing 1.25 mg of bovine serum albumin.

Analysis Note

The biological activity is measured by its ability to neutralize activin-induced erythroid differentiation on K562 cells.

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This Item
F1175E9530SRP4902
biological source

mouse

biological source

human

biological source

mouse

biological source

mouse

assay

>95% (SDS-PAGE)

assay

≥90% (SDS-PAGE)

assay

≥90% (SDS-PAGE)

assay

≥90% (SDS-PAGE)

recombinant

expressed in baculovirus infected Sf21 cells

recombinant

expressed in Sf21 cells

recombinant

expressed in NSO cells

recombinant

expressed in E. coli

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

-

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized

UniProt accession no.

P47931

UniProt accession no.

P19883

UniProt accession no.

P07321

UniProt accession no.

-


pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

wgk

WGK 1



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Global Trade Item Number

SKUGTIN
F2177-25UG04061833612804

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