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Follistatin 288 from mouse

Name: Follistatin 288 from mouse
Brand: SIGMA
Price: 493 EUR

>95% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder

Synonym(s):

FS-288

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Size/SKU	Availability	Price
25 μg	Please contact Customer Service for Availability	€580.00 €493.00

About This Item

UNSPSC Code:

51111800

NACRES:

NA.32

MDL number:

MFCD03456879

€493.00

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Properties

biological source

mouse

Quality Segment

100

recombinant

expressed in baculovirus infected Sf21 cells

assay

>95% (SDS-PAGE)

form

lyophilized powder

potency

0.04-0.4 mg per mL

mol wt

calculated mol wt ~31 kDa

packaging

pkg of 25 μg

storage condition

avoid repeated freeze/thaw cycles

impurities

endotoxin, tested

UniProt accession no.

P47931

storage temp.

−20°C

Gene Information

mouse ... Fst(14313)

Description

General description

FST (follistatin) is an activin-binding protein, and exists in two isoforms due to alternate splicing, FS288 and FS315. It is a glycoprotein with a single chain, and acts as an activin antagonist. It has a high level of expression in fetal membranes and placenta.

Biochem/physiol Actions

FST (follistatin) binds to and regulates activins, which in turn are TGF (transforming growth factor)-β superfamily members. The expression level of FST and its binding partner activin A is elevated in inflammatory disorders. The activin A-follistatin system plays an essential role in the modulation of glucose and lipid metabolism, which might have an overall effect on fetal growth. In adipose tissue, it facilitates the adipogenic differentiation of progenitor cells.

High affinity activin-binding protein that can act as an activin antagonist.

Physical form

Recombinant Mouse Follistatin 288 is supplied as a approximately 25 μg of protein lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% TFA containing 1.25 mg of bovine serum albumin.

Analysis Note

The biological activity is measured by its ability to neutralize activin-induced erythroid differentiation on K562 cells.

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This Item	F6926	SRP3045	F2302
Sigma-Aldrich F2177 Follistatin 288 from mouse	Sigma-Aldrich F6926 Fibroblast Growth Factor-8b from mouse	Sigma-Aldrich SRP3045 Follistatin human	Sigma-Aldrich F2302 Fractalkine, Chemokine Domain from mouse
description >95% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder	description >97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder	description recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture	description >97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder
assay >95% (SDS-PAGE)	assay >97% (SDS-PAGE)	assay ≥98% (HPLC), ≥98% (SDS-PAGE)	assay >97% (SDS-PAGE)
recombinant expressed in baculovirus infected Sf21 cells	recombinant expressed in E. coli	recombinant expressed in E. coli	recombinant expressed in E. coli
biological source mouse	biological source mouse	biological source human	biological source mouse
Quality Level 100	Quality Level 100	Quality Level -	Quality Level 100
form lyophilized powder	form lyophilized powder	form lyophilized	form lyophilized powder
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C

pictograms

GHS08,GHS05

signalword

Danger

hcodes

H315,H318,H361d

Hazard Classifications

Eye Dam. 1 - Repr. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

pcodes

P202 - P264 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313

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