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F3385

Fetuin from fetal bovine serum

lyophilized powder, BioReagent, suitable for cell culture

Synonym(s):

Fetuin from fetal calf serum

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Pack SizeSKUAvailabilityPrice
100 mg
Please contact Customer Service for Availability
$71.50
1 g
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$494.00
5 g
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$1,710.00
25 g
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$6,780.00

About This Item

CAS Number:
UNSPSC Code:
12352202
EC Number:
232-762-7
NACRES:
NA.75
MDL number:
Form:
lyophilized powder
Mol wt:
48.4 kDa

$71.50


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product line

BioReagent

Quality Level

form

lyophilized powder

mol wt

48.4 kDa

technique(s)

cell culture | mammalian: suitable

impurities

≤0.3% free N-acetylneuraminic acid

solubility

H2O: 1 mg/mL

storage temp.

2-8°C

General description

Fetuin from fetal bovine serum is a plasma glycoprotein. It is a 64 kDa glycoprotein, which is produced by the liver and adipose tissue.
A glycoprotein derived from FBS that is used as Fetuin has been used at a concentration of 500 mg/ml to supplement serum free F12 medium (along with insulin, transferrin and 2-mercaptoethanol) in culture of embryonal carcinoma cells.

Application

Fetuin from fetal bovine serum has been used:
  • as a substrate to determine neuraminidase activity
  • to validate the specificity of sialidases
  • to stabilize m-calpain

Biochem/physiol Actions

Fetuin acts as an inhibitor of insulin receptor tyrosine kinase. It modulates bone remodeling and calcium metabolism. Fetuin regulates vascular calcification, insulin resistance, protease activity control, keratinocytes migration and breast tumor cell proliferative signaling. It functions as a biomarker for neurodegenerative diseases. Fetuin exhibits anti-inflammatory property.

Preparation Note

Prepared by ammonium sulfate fractionation of fetal bovine serum by the method of Pederson, K.O., J. Phys. and Colloid Chem., 51, 164 (1947).

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This Item
341506F2379F3004
technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

HPLC: suitable, MALDI-MS: suitable

mol wt

48.4 kDa

mol wt

-

mol wt

-

mol wt

-

form

lyophilized powder

form

lyophilized solid

form

lyophilized powder

form

lyophilized powder

solubility

H2O: 1 mg/mL

solubility

water: 50 mg/mL

solubility

H2O: 1 mg/mL, colorless to faint yellow or tan

solubility

-

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

impurities

≤0.3% free N-acetylneuraminic acid

impurities

-

impurities

≤0.3% free N-acetylneuraminic acid

impurities

~0.2% free N-acetylneuraminic acid


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Global Trade Item Number

SKUGTIN
F3385-1G04061833613801
F3385-100MG04061833613795
F3385-25G04061833613818
F3385-5G04061833613825

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