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F6879

Ferritin from human spleen

Type V, 10 μg/mL in 0.15 M NaCl, 10 mM Tris, pH 8.0, containing 0.1% sodium azide

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1 vial
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$244.00

About This Item

CAS Number:
UNSPSC Code:
12352202
NACRES:
NA.61
MDL number:
Form:
liquid
Biological source:
human spleen

$244.00


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biological source

human spleen

Quality Segment

sterility

sterile-filtered

type

Type V

form

liquid

packaging

vial of 2 μg

concentration

10 μg/mL in 0.15 M NaCl, 10 mM Tris, pH 8.0, containing 0.1% sodium azide

UniProt accession no.

storage temp.

2-8°C

Gene Information

human ... FTH1(2495), FTL(2512)

Application

Ferritin is an iron storage protein that plays a central role in iron metabolism, and may be elevated in inflammatory or malignant diseases. It has been used in studies as an indicator of body iron supply, but may prove inaccurate in in the presence of chronic inflammation.

Biochem/physiol Actions

A ubiquitous iron storage protein that plays a key role in iron metabolism. It serves as an intracellular iron reserve (particularly in spleen, liver, intestinal mucosa, and bone marrow) and functions in iron detoxification. Studies have shown that ferritin iron incorporation is mediated by a ferroxidase activity associated with ferritin H subunits and a nucleation center associated with ferritin L subunits. Release of iron from ferritin has an essential role in iron-dependent lipid peroxidation and may contribute to free radical-induced cell damage in vivo. Therefore, by binding iron, ferritin may function as an antioxidant.

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This Item
F7879F6754SAB5700943
biological source

human spleen

biological source

horse spleen

biological source

human liver

biological source

rabbit

concentration

10 μg/mL in 0.15 M NaCl, 10 mM Tris, pH 8.0, containing 0.1% sodium azide

concentration

10 mg/mL in 0.15 M NaCl

concentration

10 μg/mL

concentration

0.5 mg/mL

form

liquid

form

liquid

form

liquid

form

liquid

UniProt accession no.

P02792, P02794

UniProt accession no.

P02791

UniProt accession no.

P02792, P02794, Q8N4E7

UniProt accession no.

P02792

Gene Information

human ... FTH1(2495), FTL(2512)

Gene Information

horse ... FTL(100051593)

Gene Information

human ... FTH1(2495), FTL(2512), FTMT(94033)

Gene Information

human ... FTL(2512)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C


Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Questions

1–2 of 2 Questions  
  1. Hello, what is the loading factor of this product? Thank you.

    1 answer
    1. The amount of iron in this product is not determined.

      Helpful?

  2. What is the volume of the ferritin solution in the vial?

    1 answer
    1. The product is supplied as a vial of 2 μg. There is 200 μL of a 10 μg/mL solution in the vial.

      Helpful?

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