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F9128

5′-(4-Fluorosulfonylbenzoyl)adenosine hydrochloride

≥95% (TLC), synthetic (organic), powder

Synonym(s):

Adenosine-5′-(4-fluorosulfonylbenzoate) hydrochloride, FSBA

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Size/SKUAvailabilityPrice
25 mg
Please contact Customer Service for Availability
$879.00

About This Item

Empirical Formula (Hill Notation):
C17H16FN5O7S · HCl
CAS Number:
78859-42-4
Molecular Weight:
489.86
NACRES:
NA.51
PubChem Substance ID:
24894988
UNSPSC Code:
41106305
MDL number:
MFCD00043258
Beilstein/REAXYS Number:
8178939
Assay:
≥95% (TLC)
Biological source:
synthetic (organic)
Form:
powder
Solubility:
methanol: 50 mg/mL, clear, colorless
Storage temp.:
−20°C

$879.00

Please contact Customer Service for Availability
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Product Name

5′-(4-Fluorosulfonylbenzoyl)adenosine hydrochloride,

biological source

synthetic (organic)

Quality Segment

assay

≥95% (TLC)

form

powder

solubility

methanol: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

Cl[H].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COC(=O)c4ccc(cc4)S(F)(=O)=O)[C@@H](O)[C@H]3O

InChI

1S/C17H16FN5O7S.ClH/c18-31(27,28)9-3-1-8(2-4-9)17(26)29-5-10-12(24)13(25)16(30-10)23-7-22-11-14(19)20-6-21-15(11)23;/h1-4,6-7,10,12-13,16,24-25H,5H2,(H2,19,20,21);1H/t10-,12-,13-,16-;/m1./s1

InChI key

ZUHVYHQVJYIHPN-KHXPSBENSA-N

Application

5′-(4-Fluorosulfonylbenzoyl)adenosine (FSBA) is an ATP analog used to study the mechanism of action of wortmannin. FSBA has been used to study vesicular transport in intestinal cells such as Caco-2, and to covalently modify residues in the nucleotide-binding domains (NBDs) of various ATPases, kinases, and other proteins.
5′-(4-Fluorosulfonylbenzoyl)adenosine hydrochloride has been used to incubate with Ime2 (inducer of meiosis 2) to determine the sensitivity of Ime2 to the adenosine triphosphate (ATP) analog 5′-fluorosulfonylbenzoyladenosine (FSBA).

Biochem/physiol Actions

5′-(4-Fluorosulfonylbenzoyl)adenosine helps to recognize adenosine triphosphate (ATP)-binding sites in kinases due to its reaction with nucleophilic amino acids happening within these motifs.

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This Item
E2387D5011CBR00093
5′-(4-Fluorosulfonylbenzoyl)adenosine hydrochloride

Sigma-Aldrich

F9128

5′-(4-Fluorosulfonylbenzoyl)adenosine hydrochloride

5′-(N-Ethylcarboxamido)adenosine powder

Sigma-Aldrich

E2387

5′-(N-Ethylcarboxamido)adenosine

5′-Deoxy-5′-(methylthio)adenosine

Sigma-Aldrich

D5011

5′-Deoxy-5′-(methylthio)adenosine

N′-(3-Aminophenyl)-N,N-dimethylsulfamide AldrichCPR

Sigma-Aldrich

CBR00093

N′-(3-Aminophenyl)-N,N-dimethylsulfamide

description

-

description

powder

description

-

description

AldrichCPR

biological source

synthetic (organic)

biological source

-

biological source

synthetic (organic)

biological source

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

-

assay

≥95% (TLC)

assay

-

assay

≥98% (HPLC)

assay

-

form

powder

form

powder

form

powder

form

solid

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

-

solubility

methanol: 50 mg/mL, clear, colorless

solubility

DMSO: 14 mg/mL (Solutions may be stored for several days at 4 °C.), 0.1 M HCl: 3.4 mg/mL (Solutions may be stored for several days at 4 °C.), ethanol: soluble (Solutions may be stored for several days at 4 °C.), H2O: insoluble, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.2 mg/mL (Solutions may be stored for several days at 4 °C.)

solubility

DMF: 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow

solubility

-

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Codes

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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