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G0897
Genistin
From Glycine max (soybean), ≥95% (HPLC), terminal deoxynucleotidyl transferase (TdT) inhibitor
Synonym(s):
4′,5,7-Trihydroxyisoflavone 7-glucoside, Genistein 7-glucoside, Genistein-7-O-β-D-glucopyranoside, Genistoside, NSC 5112
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| Size/SKU | Availability | Price |
|---|---|---|
1 mg | Check Cart for Availability | $92.20 |
5 mg | Check Cart for Availability | $321.00 |
About This Item
Empirical Formula (Hill Notation):
C21H20O10
CAS Number:
Molecular Weight:
432.38
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
64479
Assay:
≥95% (HPLC)
Product Name
Genistin, from Glycine max (soybean), ≥95% (HPLC)
biological source
Glycine max (soybean)
Quality Segment
assay
≥95% (HPLC)
solubility
DMSO: 10 mg/mL
storage temp.
−20°C
SMILES string
OC[C@H]1O[C@@H](Oc2cc(O)c3C(=O)C(=COc3c2)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O
InChI
1S/C21H20O10/c22-7-15-18(26)19(27)20(28)21(31-15)30-11-5-13(24)16-14(6-11)29-8-12(17(16)25)9-1-3-10(23)4-2-9/h1-6,8,15,18-24,26-28H,7H2/t15-,18-,19+,20-,21-/m1/s1
InChI key
ZCOLJUOHXJRHDI-CMWLGVBASA-N
Application
Biochem/physiol Actions
Inactive analog of genistein; useful as a negative control for genistein and other tyrosine kinase inhibitors.
Selective inhibitor of mammalian terminal deoxynucleotidyl transferase (TdT), with no measurable effect on mammalian or microbial DNA polymerases.
Features and Benefits
This compound is featured on the Dopamine and Norepinephrine Metabolism and Histamine Synthesis and Metabolism pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
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This Item | |||
|---|---|---|---|
| description from Glycine max (soybean), ≥95% (HPLC) | description phyproof® Reference Substance | description An isoflavone glycoside found in soy-based food products. | description United States Pharmacopeia (USP) Reference Standard |
| assay ≥95% (HPLC) | assay ≥95.0% (HPLC) | assay ≥95% (HPLC) | assay - |
| Quality Level 200 | Quality Level - | Quality Level 100 | Quality Level - |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. −20°C |
| solubility DMSO: 10 mg/mL | solubility - | solubility DMSO: 10 mg/mL | solubility - |
| biological source Glycine max (soybean) | biological source - | biological source - | biological source - |
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Storage Class
11 - Combustible Solids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, type N95 (US)
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What is the lambda max for genistin and what is the molar extinction coefficient at that wavelength?
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We have data from our QC labs here at Sigma on one of the Genistin products we offer, G0897. The solvent is 85% ethanol/15% water, and the lambda max is typically 262.0 or 262.5 nm. We measured the molar extinction coefficients at the lambda max for four different lots of G0897 back in the 1990s, and the average value was 39,800 M-1.Genistin is a derivative of Genistein. There is an entry for Genistein in the chemicals encyclopedia published by the Royal Society of Chemistry, with information for Genistin under that heading.According to the chemicals encyclopedia published by the Royal Society of Chemistry, 14th edition, entry #4391, uv max (85% ethanol) 262.5 nm (a 90.5)".The value of ""a 90.5"" is the same as an E0.1%, or the extinction coefficient for a 1 mg/mL (or 1 gram per Liter) solution.If one multiplies 90.5 (L/g) by the molecular weight of genistin (432.38 g/mole), you get 39,130 M-1. This is pretty close to the value of 39,800 from our data above."
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