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γ-Glu-Cys

Name: &#947;-Glu-Cys
Brand: SIGMA
Price: 134 USD
Availability: InStock

≥80% (HPLC), suitable for ligand binding assays

Synonym(s):

γ-L-Glutamyl-L-cysteine, des-Gly-glutathione reduced form

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Size/SKU	Availability	Price
25 mg	Available to ship TODAYfromMILWAUKEE	$134.00
100 mg	Available to ship TODAYfromMILWAUKEE	$439.00

About This Item

Empirical Formula (Hill Notation):

C₈H₁₄N₂O₅S

CAS Number:

636-58-8

Molecular Weight:

250.27

UNSPSC Code:

12352209

PubChem Substance ID:

24895030

NACRES:

NA.26

MDL number:

MFCD00237863

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Properties

Product Name

γ-Glu-Cys, ≥80% (HPLC)

Quality Segment

200

assay

≥80% (HPLC)

form

powder

composition

Peptide content, ≥60% elemental analysis

technique(s)

ligand binding assay: suitable

color

white to off-white

storage temp.

−20°C

SMILES string

N[C@@H](CCC(=O)N[C@@H](CS)C(O)=O)C(O)=O

InChI

1S/C8H14N2O5S/c9-4(7(12)13)1-2-6(11)10-5(3-16)8(14)15/h4-5,16H,1-3,9H2,(H,10,11)(H,12,13)(H,14,15)/t4-,5-/m0/s1

InChI key

RITKHVBHSGLULN-WHFBIAKZSA-N

Description

Application

γ-Glu-Cys is used to study the active sites and kinetics of glutathione synthetase(s). It has also been used for the extraction and quantification of low molecular weight thiols from Arabidopsis tissues.

Biochem/physiol Actions

γ-L-Glutamyl-L-cysteine (γ-Glu-Cys) is a substrate used for the biosynthesis of L-glutathione by glutathione synthetase(s). γ-Glu-Cys is generated by the cleavage of the Cys-Gly peptide bond of glutathione. It is also essential for the formation of phytochelatins, which are cysteine-rich thiol-reactive peptides.

Physical form

Lyophilized from 0.1% TFA.

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This Item	PHR2463	SMB01351	3541
Sigma-Aldrich G0903 γ-Glu-Cys	Supelco PHR2463 Glutathione Impurity D	Sigma-Aldrich SMB01351 γ-Glutamylphenylalanine	Sigma-Aldrich 3541 Glutathione, Reduced, Free Acid
description ≥80% (HPLC)	description certified reference material, pharmaceutical secondary standard	description ≥95% (HPLC)	description Glutathione, Reduced, Free Acid, CAS 70-18-8, is a tripeptide that serves as an endogenous antioxidant and provides protection against auto-oxidation.
form powder	form solid	form powder or crystals	form solid
assay ≥80% (HPLC)	assay -	assay ≥95% (HPLC)	assay >98% (titration)
technique(s) ligand binding assay: suitable	technique(s) -	technique(s) -	technique(s) -
storage temp. −20°C	storage temp. -10 to -25°C	storage temp. 2-8°C	storage temp. 2-8°C
Quality Level 200	Quality Level 300	Quality Level 200	Quality Level 200
color white to off-white	color -	color -	color white

Pictograms

GHS07

Signal Word

Warning

Hazard Codes

H315,H319,H335

Precautionary Statements

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves

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