This product is a multicomponent material. A single CAS number does not apply. The starting materials are α-Glycerophosphate Dehydrogenase, CAS 9075-65-4, and Triosephosphate Isomerase, CAS 9023-78-3. The ammonium sulphate CAS is 7783-20-2.
G1881
α-Glycerophosphate Dehydrogenase-Triosephosphate Isomerase from rabbit muscle
Type III, ammonium sulfate suspension
Synonym(s):
GDH/TIM, α-GDH-TPI
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| Size/SKU | Availability | Price |
|---|---|---|
250 units | Check Cart for Availability | $93.10 |
1000 units | Check Cart for Availability | $240.00 |
5000 units | Check Cart for Availability | $853.00 |
About This Item
Biological source:
rabbit muscle
biological source
rabbit muscle
Quality Segment
type
Type III
form
ammonium sulfate suspension
GDH activity
75-200 units/mg protein (biuret)
TPI activity
750-2000 units/mg protein
storage temp.
2-8°C
General description
Research area: Neuroscience
α-Glycerophosphate Dehydrogenase-Triosephosphate isomerase (α-GDH-TPI or GDH/TIM) is an enzyme mixture of α-glycerophosphate dehydrogenase (GDH) and triosephosphate isomerase (TPI).
α-Glycerophosphate Dehydrogenase-Triosephosphate isomerase (α-GDH-TPI or GDH/TIM) is an enzyme mixture of α-glycerophosphate dehydrogenase (GDH) and triosephosphate isomerase (TPI).
Application
α-Glycerophosphate Dehydrogenase-Triosephosphate Isomerase from rabbit muscle has been used in spectrophotometric aldolase assay and fructose 2,6 bisphosphate assay. It has also been used in erythrocyte transketolase (ETK) activity to study the prevalence of and factors associated with thiamin deficiency in obese.
Biochem/physiol Actions
α-glycerophosphate dehydrogenase catalyzes the conversion of dihydroxyacetone to glycerol phosphate. α-Glycerophosphate dehydrogenase (α-GPDH) has the ability to produce reactive oxygen species (ROS), that is induced by Ca2+. Triosephosphate isomerase (TPI) is an essential enzyme in the glycolytic pathway, responsible for converting dihydroxyacetone phosphate (DHAP) into glyceraldehyde-3 phosphate (GAP). TPI′s role is crucial in enhancing the efficiency of the catabolic process within glycolysis. However, a deficiency in TPI can lead to glycolytic enzymopathies, rare genetic disorders characterized by neurologic dysfunction and hemolytic anemia.
α-Glycerophosphate dehydrogenase (α-GPDH) has the ability to produce reactive oxygen species (ROS), that is induced by Ca2+.
Packaging
(Sold on the basis of α-GDH units.)
Physical form
Mixed crystalline suspension in 3.2 M (NH4)2SO4, with 0.05 g/L EDTA, pH 6.0
Other Notes
(α-GDH) One unit will convert 1.0 μmole of dihydroxyacetone phosphate to α-glycerophosphate per min at pH 7.4 at 25 °C.
(TPI) One unit will convert 1.0 μmole of D-glyceraldehyde 3-phosphate to dihydroxyacetone phosphate per min at pH 7.6 at 25 °C.
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This Item | |||
|---|---|---|---|
| description Type III, ammonium sulfate suspension | description Type III-S, ammonium sulfate suspension, ≥4,000 units/mg protein | description ammonium sulfate suspension, ≥100 units/mg protein | description ammonium sulfate suspension, 10-20 units/mg protein |
| biological source rabbit muscle | biological source rabbit muscle | biological source rabbit muscle | biological source rabbit muscle |
| form ammonium sulfate suspension | form ammonium sulfate suspension | form ammonium sulfate suspension | form ammonium sulfate suspension |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| Quality Level 200 | Quality Level 200 | Quality Level 300 | Quality Level 200 |
| GDH activity 75-200 units/mg protein (biuret) | GDH activity - | GDH activity - | GDH activity - |
| type Type III | type Type III-S | type - | type - |
Storage Class
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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