Skip to Content
MilliporeSigma

Skip To

G3126

L-Glutamine

≥99% (HPLC), ReagentPlus®

Synonym(s):

(S)-2,5-Diamino-5-oxopentanoic acid, L-Glutamic acid 5-amide, Levoglutamide

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
100 g

Available to ship TODAYfromMILWAUKEE

$102.00
250 g

Available to ship TODAYfromMILWAUKEE

$240.00
500 g

Available to ship TODAYfromMILWAUKEE

$409.00
1 kg

Available to ship TODAYfromMILWAUKEE

$732.00

About This Item

Linear Formula:
H2NCOCH2CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
146.14
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
EC Number:
200-292-1
Beilstein/REAXYS Number:
1723797

$102.00


Available to ship TODAYDetails


Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


Product Name

L-Glutamine, ReagentPlus®, ≥99% (HPLC)

Quality Segment

product line

ReagentPlus®

assay

≥99% (HPLC)

form

powder

impurities

≤0.2% free ammonia., ~0.5% Glutamic acid

color

white to off-white

mp

185 °C (dec.) (lit.)

solubility

1 M HCl: 50 mg/mL, clear to slightly hazy, colorless

cation traces

<0.2% (Ammonia (NH3))

application(s)

cell analysis
peptide synthesis

functional group

amide

storage temp.

room temp

SMILES string

N[C@@H](CCC(N)=O)C(O)=O

InChI

1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1

InChI key

ZDXPYRJPNDTMRX-VKHMYHEASA-N

Gene Information

rat ... Ggt1(116568)

General description

L-Glutamine is a versatile amino acid that plays an essential role in various metabolic processes within the human body. This non-essential amino acid is naturally abundant and contributes significantly to several vital functions. One of its primary functions is acting as the primary carrier of nitrogen in the body. It serves as the transport vehicle for nitrogen, which is a fundamental building block for many biological processes. Additionally, L-Glutamine is a major energy source for numerous types of cells, ensuring they have the energy they need to function optimally.

Moreover, L-Glutamine is essential for maintaining a delicate balance of ammonia in the body. This balance is crucial for preventing toxic ammonia levels. This amino acid facilitates the conversion of glutamic acid to glutamine, a process central to ammonia regulation. L-Glutamine is not only involved in nitrogen transport and energy production but also serves as a key player in various metabolic pathways. It participates in the biosynthesis of proteins, similar to other amino acids. Furthermore, it plays a significant role in the synthesis of urea and purines, vital components for nucleic acid production. L-Glutamine is also a vital resource for generating cellular energy, working closely with glucose for this purpose.

Another essential function of L-Glutamine is its contribution to nitrogen donation for multiple anabolic processes. These processes are vital for building crucial molecules, including purines, which are crucial for DNA production. This amino acid also provides carbon, replenishing the citric acid cycle, a central process in energy production within cells. L-Glutamine is a critical amino acid, acting as a nitrogen carrier, energy source, and contributing to protein synthesis and ammonia regulation. Its versatile functions make it a molecule of significant interest in the fields of cell biology, biochemical research, and metabolomics investigations.

Application

L-Glutamine has been used to study the effects of amino acids in promoting food consumption in Drosophila melanogaster.It has also been used to study non-enzymatic gluconeogenesis.

Biochem/physiol Actions

L-Glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.
L-glutamine is the most abundant amino acid in the body. It is essential for the synthesis of L-asparagine. L-glutamic acid aids the incorporation of NH4+ into biomolecules.

Features and Benefits

  • Can be used in Metabolomics and Biochemical research
  • High-quality compound suitable for multiple research applications

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
G639276523PHR1125
description

ReagentPlus®, ≥99% (HPLC)

description

γ-irradiated, BioXtra, suitable for cell culture

description

certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

description

Pharmaceutical Secondary Standard; Certified Reference Material

form

powder

form

powder

form

-

form

-

functional group

amide

functional group

-

functional group

-

functional group

-

assay

≥99% (HPLC)

assay

-

assay

-

assay

-

product line

ReagentPlus®

product line

BioXtra

product line

TraceCERT®

product line

-

storage temp.

room temp

storage temp.

-

storage temp.

-

storage temp.

2-30°C

mp

185 °C (dec.) (lit.)

mp

185 °C (dec.) (lit.)

mp

185 °C (dec.) (lit.)

mp

185 °C (dec.) (lit.)


Still not finding the right product?

Explore all of our products under L-Glutamine


Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library



Questions

1–5 of 5 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. Hello, It is possible to use this reagent G3126 for HPLC analysis, as standard?

    1 answer
    1. This product is not specifically tested for use as an analytical standard. However, the purity of this material is determined by HPLC. Please see the links below to review available L-Glutamine analytical standards:
      L-Glutamine, Pharmaceutical Secondary Standard
      https://www.sigmaaldrich.com/product/sial/phr1125
      L-Glutamine, certified reference material, TraceCERT
      https://www.sigmaaldrich.com/product/sial/76523

      Helpful?

  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  4. Is the molecular weight of L-Glutamine 146.14 or 146.15? The label information changed.

    1 answer
    1. Based on a molecular formula of C5H10N2O3, the molecular weight to seven significant figures is 146.1456. Over the years, this value may have been reported in Sigma-Aldrich documentation or on labels as either 146.15 (by rounding up) or 146.14 (by truncation). The material itself has not changed.

      Helpful?

  5. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

Reviews

No rating value

Active Filters