G3416
5′-Guanidinonaltrindole di(trifluoroacetate) salt hydrate
solid, ≥98% (HPLC)
Synonym(s):
GNTI
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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Check Cart for Availability | $435.00 |
About This Item
Empirical Formula (Hill Notation):
C27H29N5O3 · 2C2HF3O2 · xH2O
CAS Number:
Molecular Weight:
699.60 (anhydrous basis)
MDL number:
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
Assay:
≥98% (HPLC)
Form:
solid
Quality Segment
assay
≥98% (HPLC)
form
solid
solubility
H2O: 30 mg/mL
storage temp.
2-8°C
Gene Information
human ... OPRK1(4986)
Application
5′-Guanidinonaltrindole di(trifluoroacetate) salt hydrate (GNTI) has been used as a selective κ opioid receptor antagonist:
- to study the influence of opioid receptor types on the anti-hyperalgesic effect of dipeptidyl peptidase 4 (DPP4) inhibitors in inflammation
- to study the role of κ opioid receptor in the forebrain-dependent associative task, Whisker-Trace Eyeblink conditioning (WTEB)
- to validate its inhibitory actions on Akt kinase activities
Biochem/physiol Actions
Features and Benefits
This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Legal Information
Sold under US Patent No. 6,500,824.
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This Item | |||
|---|---|---|---|
| description solid, ≥98% (HPLC) | description ≥98% (HPLC), solid | description ≥98% (HPLC), solid | description >98% (HPLC) |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay >98% (HPLC) |
| form solid | form solid | form solid | form solid |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility H2O: 30 mg/mL | solubility H2O: >5 mg/mL | solubility DMSO: >5 mg/mL, H2O: insoluble | solubility DMSO: soluble 30 mg/mL, H2O: insoluble |
| Gene Information human ... OPRK1(4986) | Gene Information - | Gene Information - | Gene Information - |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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