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G4753

Griseofulvin

From Penicillium griseofulvum, 97.0-102.0%, Apoptosis inducer, powder

Synonym(s):

(2S)-trans-7-Chloro-2′,4,6-trimethoxy-6′-methylspiro(benzofuran-2[3H],1′-[2]cyclohexene)-3,4′-dione

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About This Item

Empirical Formula (Hill Notation):
C17H17ClO6
CAS Number:
126-07-8
Molecular Weight:
352.77
NACRES:
NA.77
PubChem Substance ID:
24895185
UNSPSC Code:
12352200
EC Number:
204-767-4
MDL number:
MFCD00082343
Beilstein/REAXYS Number:
95226
Assay:
97.0-102.0%
Form:
powder
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Product Name

Griseofulvin, from Penicillium griseofulvum, 97.0-102.0%

biological source

Penicillium griseofulvum

Quality Segment

100

assay

97.0-102.0%

form

powder

antibiotic activity spectrum

fungi

mode of action

DNA synthesis | interferes

storage temp.

−20°C

SMILES string

ClC1=C(O[C@@]2(C(OC)=CC(C[C@H]2C)=O)C3=O)C3=C(OC)C=C1OC

InChI

1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1

InChI key

DDUHZTYCFQRHIY-RBHXEPJQSA-N

Biochem/physiol Actions

Antifungal. Mode of action: Disrupts the mitotic spindle structure and inhibits nuclear division. Induces apoptosis in human tumor cell lines.

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This Item
PHR15341299007Y0002046
Griseofulvin from Penicillium griseofulvum, 97.0-102.0%

Sigma-Aldrich

G4753

Griseofulvin

Griseofulvin Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1534

Griseofulvin

Griseofulvin United States Pharmacopeia (USP) Reference Standard

USP

1299007

Griseofulvin

Griseofulvin for LC assay and identification European Pharmacopoeia (EP) Reference Standard

Y0002046

Griseofulvin for LC assay and identification

description

from Penicillium griseofulvum, 97.0-102.0%

description

Pharmaceutical Secondary Standard; Certified Reference Material

description

United States Pharmacopeia (USP) Reference Standard

description

European Pharmacopoeia (EP) Reference Standard

assay

97.0-102.0%

assay

-

assay

-

assay

-

form

powder

form

-

form

-

form

-

Quality Level

100

Quality Level

300

Quality Level

-

Quality Level

-

storage temp.

−20°C

storage temp.

-10 to -25°C

storage temp.

2-8°C

storage temp.

−20°C

mode of action

DNA synthesis | interferes

mode of action

-

mode of action

-

mode of action

-

biological source

Penicillium griseofulvum

biological source

-

biological source

-

biological source

-

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pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Carc. 2 - Repr. 1B - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

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