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Anti-GAD67 Antibody

Name: Anti-GAD67 Antibody
Brand: SIGMA
Price: 650 USD

clone K-87, purified antibody

Synonym(s):

Anti-GAD 67

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Size/SKU	Availability	Price
100 μg	Check Cart for Availability	$650.00

About This Item

MDL number:

MFCD06202147

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

K-87, monoclonal

Application:

IHC (p), WB

Citations:

$650.00

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Properties

Product Name

Monoclonal Anti-Glutamic Acid Decarboxylase 67 (GAD67) antibody produced in mouse, clone K-87, purified antibody

biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

K-87, monoclonal

mol wt

antigen 67 kDa

species reactivity

rat, mouse, human

concentration

~1 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:500-1:20,000 (with antigen-retrieval step), western blot: 1:500-1:20,000 using mouse brain extract

isotype

IgG1κ

UniProt accession no.

Q99259

shipped in

dry ice

storage temp.

−70°C

target post-translational modification

unmodified

Gene Information

human ... GAD1(2571)
mouse ... Gad1(14415)
rat ... Gad1(24379)

Description

General description

Glutamic Acid Decarboxylase 67 (GAD67) is encoded by the gene glutamic acid decarboxylase 1 (GAD1). GAD1 gene is located on the human chromosome at 2q31.1. GAD67 is localized in the dendrites and cell bodies.

Immunogen

This peptide does not share homology with GAD65.

synthetic peptide from mouse GAD67 (amino acids 87-106).

Application

Monoclonal anti-glutamic acid decarboxylase 67 (GAD67) antibody produced in mouse has been used in:

immunohistofluorescence
western blotting
immunohistochemistry.

Monoclonal Anti-Glutamic Acid Decarboxylase 67 (GAD67) antibody is suitable for use in immunoblot, western blot (at 1:500-1:20,000 dilutions using mouse brain extract) and immunohistochemistry (at 1:500-1:20,000 dilutions in mouse brain sections).

Biochem/physiol Actions

Glutamic Acid Decarboxylase 67 (GAD67) is involved in the production of γ-amino butyric acid (GABA), a inhibitory neurotransmitter in the central nervous system (CNS). Deficiency of GAD67 leads to psychosis, schizophrenia and bipolar diseases.

Reacts specifically with GAD67. Does not crossreact with GAD65.

Physical form

Solution in phosphate buffered saline containing 0.01% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Show Differences

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This Item	ZMS5406	MAB5406B	SAB4501074
Sigma-Aldrich G5419 Monoclonal Anti-Glutamic Acid Decarboxylase 67 (GAD67) antibody produced in mouse	Sigma-Aldrich ZMS5406 Anti-GAD67 Antibody, clone 1G10.2 ZooMAb^® Mouse Monoclonal	Sigma-Aldrich MAB5406B Anti-GAD67 Antibody, clone 1G10.2, Biotin Conjugate	Sigma-Aldrich SAB4501074 Anti-GAD1 antibody produced in rabbit
description clone K-87, purified antibody	description recombinant, expressed in HEK 293 cells	description clone 1G10.2, from mouse, biotin conjugate	description affinity isolated antibody
antibody form purified antibody	antibody form purified antibody	antibody form purified immunoglobulin	antibody form affinity isolated antibody
species reactivity rat, mouse, human	species reactivity mouse, rat	species reactivity rat	species reactivity mouse, human, rat
Gene Information human ... GAD1(2571) mouse ... Gad1(14415) rat ... Gad1(24379)	Gene Information human ... GAD1(2571)	Gene Information human ... GAD1(2571)	Gene Information human ... GAD1(2571)
biological source mouse	biological source mouse (recombinant)	biological source mouse	biological source rabbit
clone K-87, monoclonal	clone monoclonal, 1G10.2, recombinant monoclonal	clone 1G10.2, monoclonal	clone polyclonal
conjugate unconjugated	conjugate unconjugated	conjugate biotin conjugate	conjugate unconjugated

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Storage Class

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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