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Gallamine triethiodide

≥98% (TLC), allosteric muscarinic receptor antagonist, powder

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5 g

Available to ship TODAYfromMILWAUKEE

$198.00
$205.00
25 g

Available to ship TODAYfromMILWAUKEE

$724.00
$615.40

About This Item

Empirical Formula (Hill Notation):
C30H60I3N3O3
CAS Number:
Molecular Weight:
891.53
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352116
EC Number:
200-605-1
MDL number:
Assay:
≥98% (TLC)
Form:
powder

$205.00

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Product Name

Gallamine triethiodide, ≥98% (TLC), powder, muscarinic receptor antagonist

Quality Segment

assay

≥98% (TLC)

form

powder

mp

235 °C (dec.) (lit.)

solubility

H2O: 100 mg/mL, ethanol: soluble

storage temp.

2-8°C

SMILES string

[I-].[I-].[I-].CC[N+](CC)(CC)CCOc1cccc(OCC[N+](CC)(CC)CC)c1OCC[N+](CC)(CC)CC

InChI

1S/C30H60N3O3.3HI/c1-10-31(11-2,12-3)22-25-34-28-20-19-21-29(35-26-23-32(13-4,14-5)15-6)30(28)36-27-24-33(16-7,17-8)18-9;;;/h19-21H,10-18,22-27H2,1-9H3;3*1H/q+3;;;/p-3

InChI key

REEUVFCVXKWOFE-UHFFFAOYSA-K

Application

Gallamine triethiodide has been used:
  • as a relaxant for measuring spinal trigeminal nucleus recordings from single neurons.
  • as an antagonist in neuroblastoma cells as M2 receptor
  • to reduce eye movement during retinal surgery in rat

Biochem/physiol Actions

Gallamine triethiodide has anti-muscarinic effect. It is a competitive antagonist for the muscarinic receptor. Gallamine is regarded as neuromuscular blocking agent.
Muscle relaxant; allosteric muscarinic receptor antagonist with an order of potency of M2 > M1 = M4 > M3 = M5. Ligand for the peripheral anionic binding site of acetylcholinesterase.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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This Item
PHR1118PHL82592
description

≥98% (TLC), powder, muscarinic receptor antagonist

description

Pharmaceutical Secondary Standard; Certified Reference Material

description

phyproof® Reference Substance

form

powder

form

-

form

-

assay

≥98% (TLC)

assay

-

assay

≥90.0% (HPLC)

Quality Level

200

Quality Level

300

Quality Level

-

storage temp.

2-8°C

storage temp.

2-30°C

storage temp.

-

solubility

H2O: 100 mg/mL, ethanol: soluble

solubility

-

solubility

-

mp

235 °C (dec.) (lit.)

mp

146-149 °C (lit.)

mp

-


Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

WGK

WGK 3

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves



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