This product is tested for solubility in methanol at 20 mg/mL. However, historical data indicates that the material is soluble up to 49 mg/mL in methanol. For use in cell culture, similar rates are expected in ethanol. Stock solutions may be stored in aliquots at -20°C.
H5142
20-Hydroxyecdysone
≥93% (HPLC), ecdysteroid hormone, powder
Synonym(s):
β-Ecdysone, 2β,3β,14α,20β,22,25-Hexahydroxy-7-cholesten-6-one, Ecdysterone, Insect moulting hormone, Polypodine A
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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Check Cart for Availability | $217.00 |
10 mg | Check Cart for Availability | $413.00 |
25 mg | Check Cart for Availability | $896.00 |
About This Item
Empirical Formula (Hill Notation):
C27H44O7
CAS Number:
Molecular Weight:
480.63
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
1917578
Assay:
≥93% (HPLC)
Form:
powder
Product Name
20-Hydroxyecdysone, ≥93% (HPLC), powder
sterility
non-sterile
Quality Segment
assay
≥93% (HPLC)
form
powder
color
white to off-white
solubility
alcohol: soluble
application(s)
agriculture
environmental
shipped in
ambient
storage temp.
−20°C
SMILES string
[H][C@]12CC[C@]3(C)[C@H](CC[C@@]3(O)C1=CC(=O)[C@]4([H])C[C@@H](O)[C@@H](O)C[C@]24C)[C@@](C)(O)[C@H](O)CCC(C)(C)O
InChI
1S/C27H44O7/c1-23(2,32)9-8-22(31)26(5,33)21-7-11-27(34)16-12-18(28)17-13-19(29)20(30)14-24(17,3)15(16)6-10-25(21,27)4/h12,15,17,19-22,29-34H,6-11,13-14H2,1-5H3/t15-,17-,19+,20-,21-,22+,24+,25+,26+,27+/m0/s1
InChI key
NKDFYOWSKOHCCO-YPVLXUMRSA-N
Application
20-Hydroxyecdysone has been used:
- in Leibovitz′s dissecting medium for culturing sorting zone and neuropil-associated glia and antennal lobes of Manduca sexta
- in Schneider′s medium to reproduce ex-vivo imaginal disc eversion
- as a supplement in Mcl8 medium for culturing Drosophila wing imaginal discs
Biochem/physiol Actions
20-Hydroxyecdysone is an ecdysteroid hormone that plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene expression involved in molting and metamorphosis. It acts through a heterodimeric receptor comprising the ecdysone receptor and the ultraspiracle proteins (USP).
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This Item | |||
|---|---|---|---|
| description ≥93% (HPLC), powder | description ≥90% | description ≥65% | description ≥98% (HPLC) |
| assay ≥93% (HPLC) | assay ≥90% | assay - | assay ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| Quality Level 100 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C |
| solubility alcohol: soluble | solubility methanol: 20 mg/mL, clear, colorless to faintly yellow | solubility ethanol: soluble | solubility DMSO: ≥15 |
| color white to off-white | color - | color - | color white to tan |
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Inquiry About 20-Hydroxyecdysone Preparation Dear company, I have been ordering 20-Hydroxyecdysone for use as a supplement in insect cell culture. Could you kindly share the preparation and dissolving procedure with me? Sincerely,
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