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L-Homoserine

Name: <SC>L</SC>-Homoserine
Brand: SIGMA

Synonym(s):

(S)-2-Amino-4-hydroxybutyric acid, Hse

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About This Item

Linear Formula:

HOCH₂CH₂CH(NH₂)CO₂H

CAS Number:

672-15-1

Molecular Weight:

119.12

NACRES:

NA.26

PubChem Substance ID:

24895748

eCl@ss:

32160406

UNSPSC Code:

12352209

EC Number:

211-590-6

MDL number:

MFCD00063090

Beilstein/REAXYS Number:

1721681

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Properties

assay

≥98% (TLC)

Quality Segment

100

form

powder

color

white to off-white

mp

203 °C (dec.) (lit.)

application(s)

cell analysis
detection

SMILES string

N[C@@H](CCO)C(O)=O

InChI

1S/C4H9NO3/c5-3(1-2-6)4(7)8/h3,6H,1-2,5H2,(H,7,8)/t3-/m0/s1

InChI key

UKAUYVFTDYCKQA-VKHMYHEASA-N

Description

General description

L-Homoserine is a variant of serine with an additional carbon on its side chain.

Application

L-Homoserine has been used as an internal standard for neurotransmitter analysis and amino acids quantification.

Biochem/physiol Actions

L-Homoserine is used in the biosynthesis of methionine, threonine and isoleucine.

L-Homoserine is synthesized by deoxidation process, catalysed by homoserine dehydrogenase. This is one of the steps in the synthesis of L-threonine. The carbon flux in in bacteria such as E. coli is maintained by this reaction.

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This Item	69453	O9014	03694
Sigma-Aldrich H6515 L-Homoserine	Sigma-Aldrich 69453 L-Homocysteine	Sigma-Aldrich O9014 N-(3-Oxodecanoyl)-L-homoserine lactone	Sigma-Aldrich 03694 L-β-Homoserine
description -	description ≥98.0% (NT)	description -	description ≥98.0% (TLC)
form powder	form powder	form powder	form powder or crystals
assay ≥98% (TLC)	assay ≥98.0% (NT)	assay ≥98% (TLC)	assay ≥98.0% (TLC)
mp 203 °C (dec.) (lit.)	mp 263-265 °C	mp -	mp -
color white to off-white	color white	color white	color white to off-white
Quality Level 100	Quality Level 100	Quality Level 200	Quality Level 100
application(s) cell analysis detection	application(s) cell analysis	application(s) cell analysis	application(s) peptide synthesis

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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