H6660
HIV Protease Substrate 1
≥95% (HPLC), powder
Synonym(s):
Arg-Glu(EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg
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| Size/SKU | Availability | Price |
|---|---|---|
1 mg | Please contact Customer Service for Availability | $754.00 |
About This Item
$754.00
Please contact Customer Service for Availability
Product Name
HIV Protease Substrate 1,
assay
≥95% (HPLC)
Quality Segment
form
powder
mol wt
2016
solubility
DMSO: soluble
storage temp.
−20°C
Application
Biochem/physiol Actions
Substrate for endopeptidases
HIV Protease Substrate 1 is a synthetic peptide sequence that contains the cleavage site (Tyr-Pro) for the human immunodeficiency virus (HIV) Protease. It has two covalently modified amino acids for the detection of cleavage. One modification is the addition of the fluorophore 5-(2-aminoethylamino)-1-naphthalene sulfonate (EDANS) to the glutamic acid residue, while the other one includes the addition of the acceptor chromophore 4c-dimethylaminoazobenzene-4-carboxylate (DABCYL) to the lysine residue. The modified amino acids are on opposite sides of the cleavage site. Spatial orientation and overlap of the DABCYL absorbance with the EDANS emission permit resonance energy transfer between the two moieties. However, when the peptide is cleaved by the HIV protease, the DABCYL group is no longer proximal to the fluorophore.
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This Item | |||
|---|---|---|---|
| description - | description ≥95% (HPLC) | description ≥95% (HPLC) | description ≥95% (HPLC) |
| assay ≥95% (HPLC) | assay ≥95% (HPLC) | assay ≥95% (HPLC) | assay ≥95% (HPLC) |
| solubility DMSO: soluble | solubility H2O: >1 mg/mL | solubility - | solubility - |
| Quality Level 200 | Quality Level 100 | Quality Level 200 | Quality Level 100 |
| form powder | form lyophilized | form powder | form powder |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| mol wt 2016 | mol wt - | mol wt - | mol wt - |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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