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H6891

7β-Hydroxycholesterol

≥95%

Synonym(s):

5-Cholestene-3β,7β-diol

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Size/SKUAvailabilityPrice
1 mg

Available to ship TODAY

$234.00
5 mg

Estimated to ship onDecember 02, 2026

$759.00

About This Item

Empirical Formula (Hill Notation):
C27H46O2
CAS Number:
Molecular Weight:
402.65
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352211
MDL number:

$234.00


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Quality Segment

assay

≥95%

form

powder

functional group

hydroxyl

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)C3=C[C@@H]2O)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCCC(C)C

InChI

1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-25,28-29H,6-15H2,1-5H3

InChI key

OYXZMSRRJOYLLO-UHFFFAOYSA-N

Application

7β-hydroxycholesterol was used to study oxysterol-induced apoptosis in human endothelial cells.

Biochem/physiol Actions

7β-Hydroxycholesterol is an oxysterol, the enzymatic or non-enzymatic product of cholesterol oxidation. Oxysterols are cytotoxic and induce death in monocytes, smooth muscle cells and endothelial cells. The mechanism of apoptosis induced by oxysterols may involve caspases or DNA fragmentation. Increased levels of 7β-Hydroxycholesterol correlates with increased risk of cardiovascular diseases including atherosclerosis.

Preparation Note

7β-Hydroxycholesterol yields clear, colorless to faint yellow solution in ethanol, with or without heating.

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This Item
H5884H6378733334
description

≥95%

description

-

description

analytical standard

description

99 atom % 13C, 98% (CP)

assay

≥95%

assay

≥98% (TLC)

assay

≥98%

assay

98% (CP)

functional group

hydroxyl

functional group

-

functional group

-

functional group

-

form

powder

form

powder

form

-

form

solid

shipped in

ambient

shipped in

ambient

shipped in

-

shipped in

-

storage temp.

room temp

storage temp.

room temp

storage temp.

-

storage temp.

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

-


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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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