Skip to Content
MilliporeSigma

Key Documents

View All Documentation

Skip To

H6894

[Tyr(SO3H)63]-Hirudin Fragment 54-65

≥95% (HPLC)

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
0.1 mg
Check Cart for Availability
$191.00

About This Item

Empirical Formula (Hill Notation):
C66H93N13O28S
CAS Number:
109528-49-6
Molecular Weight:
1548.58
NACRES:
NA.32
PubChem Substance ID:
24895775
UNSPSC Code:
12352209
MDL number:
MFCD00076564
Form:
powder
Assay:
≥95% (HPLC)
Biological source:
synthetic (organic)

$191.00

Check Cart for Availability
​
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

synthetic (organic)

Quality Segment

assay

≥95% (HPLC)

form

powder

storage temp.

−20°C

SMILES string

CCC(C)C(NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(Cc1ccccc1)NC(=O)C(CC(O)=O)NC(=O)CN)C(=O)N2CCCC2C(=O)NC(CCC(O)=O)C(=O)NC(CCC(O)=O)C(=O)NC(Cc3ccc(OS(O)(=O)=O)cc3)C(=O)NC(CC(C)C)C(=O)NC(CCC(N)=O)C(O)=O

InChI

1S/C66H93N13O28S/c1-5-34(4)55(78-59(95)41(21-26-53(88)89)71-56(92)38(18-23-50(82)83)72-61(97)44(29-35-10-7-6-8-11-35)77-63(99)46(31-54(90)91)69-49(81)32-67)65(101)79-27-9-12-47(79)64(100)73-40(20-25-52(86)87)57(93)70-39(19-24-51(84)85)58(94)76-45(30-36-13-15-37(16-14-36)107-108(104,105)106)62(98)75-43(28-33(2)3)60(96)74-42(66(102)103)17-22-48(68)80/h6-8,10-11,13-16,33-34,38-47,55H,5,9,12,17-32,67H2,1-4H3,(H2,68,80)(H,69,81)(H,70,93)(H,71,92)(H,72,97)(H,73,100)(H,74,96)(H,75,98)(H,76,94)(H,77,99)(H,78,95)(H,82,83)(H,84,85)(H,86,87)(H,88,89)(H,90,91)(H,102,103)(H,104,105,106)

InChI key

CKXMQSIWBKKXGT-UHFFFAOYSA-N

Application

[Tyr(SO3H)63]-hirudin fragment 54-65 has been used to study the effect of thrombin in presence of leupeptin. It is also used to study the effect of hirudin peptide on the thrombin-rHCII (recombinant heparin cofactor II)-L444R (leucine 444 to arginine) complex separation.

Biochem/physiol Actions

Hirudin fragment that binds to the regulatory exosite I on thrombin and the regulatory proexosite I on prothrombin.
Hirudin fragment that binds to the regulatory exosite I on thrombin and the regulatory proexosite I on prothrombin. The interaction with thrombin prevents the thrombin-induced activation of clotting factor V. The interaction with prothrombin inhibits the formation of thrombin by factor Xa in the presence of factor Va.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
H9019H7016H0393
[Tyr(SO3H)63]-Hirudin Fragment 54-65 ≥95% (HPLC)

Sigma-Aldrich

H6894

[Tyr(SO3H)63]-Hirudin Fragment 54-65

Ac-Hirudin Fragment 55-65 non-sulfated ≥97% (HPLC)

Sigma-Aldrich

H9019

Ac-Hirudin Fragment 55-65 non-sulfated

Hirudin from leeches lyophilized powder, ≥1,500 ATU/mg protein (ATU = antithrombin units)

Sigma-Aldrich

H7016

Hirudin from leeches

Hirudin recombinant, expressed in unspecified host, ≥7,000 ATU/mg protein (ATU = antithrombin units)

Sigma-Aldrich

H0393

Hirudin

description

≥95% (HPLC)

description

≥97% (HPLC)

description

lyophilized powder, ≥1,500 ATU/mg protein (ATU = antithrombin units)

description

recombinant, expressed in unspecified host, ≥7,000 ATU/mg protein (ATU = antithrombin units)

biological source

synthetic (organic)

biological source

-

biological source

animal (Hirudo verbana)

biological source

-

assay

≥95% (HPLC)

assay

≥97% (HPLC)

assay

-

assay

-

form

powder

form

-

form

lyophilized powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Questions

Reviews

No rating value

Active Filters