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H8283

Hemocyanin from Megathura crenulata (keyhole limpet)

PBS solution

Synonym(s):

KLH, Keyhole limpet hemocyanin

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50 mg

Available to ship TODAYfromMILWAUKEE

$169.00
100 mg

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$287.00
500 mg

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$1,040.00

About This Item

CAS Number:
9013-72-3
UNSPSC Code:
12352202
NACRES:
NA.25
MDL number:
MFCD00131280
Form:
PBS solution
Biological source:
Megathura crenulata

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biological source

Megathura crenulata

Quality Segment

300

form

PBS solution

concentration

3.0-7.0 mg/mL protein (A280)

copper content

0.10-0.30% (based on protein)

technique(s)

ELISA: suitable

storage temp.

2-8°C

General description

Gastropod hemocyanins are massive glycoproteins (4 to 8 MDa) designed by an intricate arrangement of 10 subunits that are self-assembled into hollow cylinders 35 nm in diameter.
Hemocyanin is a high molecular weight copper containing glycoprotein. It reversibly binds oxygen and forms the extra-cellular respiratory protein of mollusks. Keyhole limpet hemocyanin (KLH) is filtered from the hemolymph of Megathura crenulata, also called the giant keyhole limpet. It is native to the southern California coast and Mexico.

Application

Keyhole limpet hemocyanin (KLH) is a strong and well known immune-stimulant in both experimental animals and humans. It has been used as a hapten carrier protein to enhance antigen-specific T cell priming and is known to stimulate a CD4+ T-cell response.
Hemocyanin was used to study if antipeptide antibodies specifically recognize the l1 protein of the human papilloma virus of type 31. It was also used to study the acid-induced unfolding of didecameric keyhole limpet hemocyanin.

Physical form

Solution in PBS, pH 7.2, containing 1mM CaCl2 and 0.5 mM MgCl2 with 15 mM sodium azide as preservative

Preparation Note

Chromatographically purified.

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Hemocyanin from Megathura crenulata (keyhole limpet) PBS solution

Sigma-Aldrich

H8283

Hemocyanin from Megathura crenulata (keyhole limpet)

Hemocyanin, Keyhole Limpet, Megathura crenulata Hemocyanin, Keyhole Limpet, Megathura crenulata, CAS 9013-72-3, is a large, multi-subunit, oxygen-carrying, metalloprotein that is used as a carrier protein in the production of antibodies.

Sigma-Aldrich

374805

Hemocyanin, Keyhole Limpet, Megathura crenulata

Hemocyanin, Keyhole Limpet, Megathura crenulata, High Purity, Endotoxin-Free, Sterile-Liquid Hemocyanin, Keyhole Limpet, Megathura crenulata, High Purity, Endotoxin Free, is a large, multi-subunit, O2-carrying, metalloprotein that is used as a carrier protein in the production of antibodies.

Sigma-Aldrich

374825

Hemocyanin, Keyhole Limpet, Megathura crenulata, High Purity, Endotoxin-Free, Sterile-Liquid

Hemocyanin, Keyhole Limpet, Megathura crenulata, BES/Mg2+ Buffer Hemocyanin, Keyhole Limpet, Megathura crenulata, BES/Mg2+ buffer, CAS 9013-72-3, is a large, multi-subunit, O2-carrying, metalloprotein that is used in the production of antibodies.

Sigma-Aldrich

374807

Hemocyanin, Keyhole Limpet, Megathura crenulata, BES/Mg2+ Buffer

description

PBS solution

description

Hemocyanin, Keyhole Limpet, Megathura crenulata, CAS 9013-72-3, is a large, multi-subunit, oxygen-carrying, metalloprotein that is used as a carrier protein in the production of antibodies.

description

Hemocyanin, Keyhole Limpet, Megathura crenulata, High Purity, Endotoxin Free, is a large, multi-subunit, O2-carrying, metalloprotein that is used as a carrier protein in the production of antibodies.

description

Hemocyanin, Keyhole Limpet, Megathura crenulata, BES/Mg2+ buffer, CAS 9013-72-3, is a large, multi-subunit, O2-carrying, metalloprotein that is used in the production of antibodies.

biological source

Megathura crenulata

biological source

-

biological source

-

biological source

Megathura crenulata

technique(s)

ELISA: suitable

technique(s)

-

technique(s)

-

technique(s)

-

concentration

3.0-7.0 mg/mL protein (A280)

concentration

-

concentration

-

concentration

-

form

PBS solution

form

lyophilized solid

form

liquid

form

liquid

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Quality Level

300

Quality Level

200

Quality Level

200

Quality Level

100

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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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