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H8876

5-Hydroxyindole-3-acetic acid

≥98% (HPLC), crystalline

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Synonym(s):

5-HIAA

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100 mg

Available to ship TODAYfromMILWAUKEE

$39.70
500 mg

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$113.00
1 g

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$196.00

About This Item

Empirical Formula (Hill Notation):
C10H9NO3
CAS Number:
Molecular Weight:
191.18
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
200-195-4
MDL number:
Beilstein/REAXYS Number:
168797
Assay:
≥98% (HPLC)
Form:
crystalline

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Product Name

5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline

Quality Segment

assay

≥98% (HPLC)

form

crystalline

color

white to purple

mp

161-164 °C (dec.) (lit.)

storage temp.

−20°C

SMILES string

OC(=O)Cc1c[nH]c2ccc(O)cc12

InChI

1S/C10H9NO3/c12-7-1-2-9-8(4-7)6(5-11-9)3-10(13)14/h1-2,4-5,11-12H,3H2,(H,13,14)

InChI key

DUUGKQCEGZLZNO-UHFFFAOYSA-N

General description

5-Hydroxyindole-3-acetic acid (5-HIAA) is the catabolic end product of serotonin pathway. 5-HIAA is present in body fluids like cerebrospinal fluid (CSF), blood and urine. The expression levels of 5-HIAA is different among the normal and cancer patients. Sepiapterin reductase deficiency results in low level of 5-HIAA in CSF. 5-HIAA level is low in CSF in patients with bipolar 1 disorder with childhood attention-deficit hyperactivity disorder (ADHD).

Application

5-Hydroxyindole-3-acetic acid has been used as standard for the measurement of 5-HIAA in the brain tissue of mice using high performance liquid chromatography (HPLC).

Biochem/physiol Actions

Major serotonin metabolite.

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description

≥98% (HPLC), crystalline

description

analytical standard

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description

PESTANAL®, analytical standard

assay

≥98% (HPLC)

assay

≥98% (HPLC), ≥98% (T)

assay

≥95% (NMR)

assay

98%

form

crystalline

form

-

form

solid

form

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Quality Level

200

Quality Level

-

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

-

color

white to purple

color

-

color

white to pale yellow

color

-

mp

161-164 °C (dec.) (lit.)

mp

161-164 °C (dec.) (lit.)

mp

-

mp

165-169 °C (lit.)


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Questions

  1. Avec quel produit il est préférable de le resuspendre le 5-HIAA?

    1 answer
    1. This product is tested in-house for solubility in ethanol at 50 mg/ml. Other sources report solubility in DMSO at a concentration of approximately 25 mg/ml.

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