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IL-3 human

Name: IL-3 human
Brand: SIGMA
Price: 330 USD
Availability: InStock

≥97% (HPLC and SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Synonym(s):

Interleukin-3 human, hIL-3, IL-3

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10 μg	Check Cart for Availability	$330.00

About This Item

UNSPSC Code:

12352202

NACRES:

NA.77

MDL number:

MFCD00147276

Biological source:

human

Recombinant:

expressed in E. coli

Assay:

≥97% (HPLC and SDS-PAGE)

Form:

lyophilized powder

Mol wt:

15 kDa

Impurities:

≤0.1 EU/μg

$330.00

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Properties

Product Name

Interleukin-3 human, IL-3, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

biological source

human

Quality Segment

200

recombinant

expressed in E. coli

assay

≥97% (HPLC and SDS-PAGE)

form

lyophilized powder

potency

≤1.0 ng/mL ED₅₀/EC₅₀

quality

endotoxin tested

mol wt

15 kDa

packaging

pkg of 10 and 50 μg

storage condition

avoid repeated freeze/thaw cycles

technique(s)

cell culture | mammalian: suitable

impurities

≤0.1 EU/μg

UniProt accession no.

P08700

storage temp.

−20°C

Description

Biochem/physiol Actions

Interleukin-3 (IL-3) is a multifunctional protein, originally called colony forming unit-stimulating activity (CFU-SA), and is produced by activated T lymphocytes. IL-3 supports the formation of multilineage colonies in the early development of multipotent hematopoietic progenitor cells. IL-3 has been shown to induce colony formation of macrophages, neutrophils, mast cells, and megakaryocytes from agar-suspended bone marrow cells. IL-3 also interacts with IL-2 to stimulate growth of T lymphocytes and to induce IgG secretion from activated B cells. Other synonyms for IL-3 include pan-specific hemopoietin, multicolony stimulating factor, mast cell growth factor, burst promoting activity, histamine-producing cell stimulating factor, P cell stimulating factor, and WEHI-3 factor.

Interleukin-3 is a multifunctional protein produced by activated T lymphocytes. IL-3 supports the formation of multilineage colonies in the early development of multipotent hematopoietic progenitor cells. IL-3 also interacts with IL-2 to stimulate growth of T lymphocytes and induce IgG secretion from activated B cells.

Physical form

Lyophilized with no additives. Sterile filtered through a 0.2 μm filter.

Analysis Note

The biological activity is measured by the dose-dependent stimulation of the proliferation of human TF-1 cells.

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This Item	I1395	I4269	SCU0001
Sigma-Aldrich I1646 Interleukin-3 human	Sigma-Aldrich I1395 Interleukin-6 human	Sigma-Aldrich I4269 Interleukin-4 human	Sigma-Aldrich SCU0001 Interleukin-6 human
description IL-3, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture	description IL-6, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture	description IL-4, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture	description recombinant, expressed in HEK 293 cells, suitable for cell culture
technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable
recombinant expressed in E. coli	recombinant expressed in E. coli	recombinant expressed in E. coli	recombinant expressed in HEK 293 cells
biological source human	biological source human	biological source human	biological source human
assay ≥97% (HPLC and SDS-PAGE)	assay ≥97% (SDS-PAGE)	assay ≥98% (SDS-PAGE)	assay ≥98% (SDS-PAGE)
Quality Level 200	Quality Level 300	Quality Level 200	Quality Level 200
form lyophilized powder	form lyophilized powder	form lyophilized powder	form lyophilized powder

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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves

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