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Anti-Interleukin-6 antibody produced in rabbit

Name: Anti-Interleukin-6 antibody produced in rabbit
Brand: SIGMA
Price: 416 USD
Availability: InStock

IgG fraction of antiserum, buffered aqueous solution

Synonym(s):

Anti-IL-6

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Size/SKU	Availability	Price
100 μL	Check Cart for Availability	$416.00

About This Item

UNSPSC Code:

51111800

NACRES:

NA.41

MDL number:

MFCD00162579

Conjugate:

unconjugated

Clone:

polyclonal

Application:

Neutral, RIA

Citations:

$416.00

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Properties

biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

neutralization: suitable using human IL-6 in a T1165 cell proliferation bioassay, radioimmunoassay: suitable

UniProt accession no.

P05231

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... IL6(3569)

Description

General description

Anti-Interleukin 6 (IL-6) is produced in rabbit using purified human recombinant IL-6 produced in E. coli as the immunogen. Interleukin-6 is a multifunctional protein originally discovered in the media of cells stimulated with double stranded RNA. Interleukin-6 (IL-6) is a cytokine produced by activated T cells, endothelial cells, fibroblasts and activated monocytes or macrophages.

Immunogen

Purified human recombinant IL-6 produced in E. coli.

Application

Anti-Interleukin-6 antibody can be used in western blotting and ELISA for studying human IL-6. It can also be used for dot blot immunoassay. Anti-Interleukin-6 antibody can be used for selective neutralization of human IL-6 bioactivity in cell culture. It can also be used in radioimmunoassay (RIA) (diluted 1:60,000).

It may also be used in immunoblotting.

Biochem/physiol Actions

Interleukin 6 (IL-6) acts upon a variety of cells, including fibroblasts, myeloid progenitor cells, T cells, B cells, and hepatocytes. Interleukin 6 (IL-6) also potentiates the proliferative effect of Interleukin 3 (IL-3) on multipotential hematopoietic progenitors.

Interleukin-6 (IL-6) is a cytokine produced by activated T cells, endothelial cells, fibroblasts and activated monocytes or macrophages. It plays a crucial role in regulating the acute phase response as well as responses occurs after injury and infection. It interacts with IL-2 and facilitates in the proliferation of T lymphocytes.

The antibody will neutralize the biological activity of human IL-6 in cell culture. The antibody does not cross-react with human IL-1β, TNF-α or mouse IL-6.

Physical form

Solution, 0.2 μm filtered, in 0.5 mL phosphate buffered saline, pH 7.4.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	I7901	I8273	I5270
$Anti-Interleukin-6 antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution$ Sigma-Aldrich I2143 Anti-Interleukin-6 antibody produced in rabbit	Sigma-Aldrich I7901 Monoclonal Anti-Interleukin-6 antibody produced in mouse	$Anti-Interleukin-2 antibody produced in goat IgG fraction of antiserum, lyophilized powder$ Sigma-Aldrich I8273 Anti-Interleukin-2 antibody produced in goat	$Anti-Interleukin-11 antibody produced in goat IgG fraction of antiserum, lyophilized powder$ Sigma-Aldrich I5270 Anti-Interleukin-11 antibody produced in goat
description IgG fraction of antiserum, buffered aqueous solution	description clone 6708.11, purified immunoglobulin, lyophilized powder	description IgG fraction of antiserum, lyophilized powder	description IgG fraction of antiserum, lyophilized powder
biological source rabbit	biological source mouse	biological source goat	biological source goat
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form IgG fraction of antiserum	antibody form purified immunoglobulin	antibody form IgG fraction of antiserum	antibody form IgG fraction of antiserum
Quality Level 200	Quality Level 200	Quality Level 100	Quality Level 100
UniProt accession no. P05231	UniProt accession no. P05231	UniProt accession no. P60568	UniProt accession no. P20809
form buffered aqueous solution	form lyophilized powder	form lyophilized powder	form lyophilized powder

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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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