Key Documents

View All Documentation

Sodium iodoacetate

Name: Sodium iodoacetate
Brand: SIGMA
Price: 261 USD
Availability: InStock

powder, ≥98%

Synonym(s):

Iodoacetic acid sodium salt

Select a Size

Change View

Size/SKU	Availability	Price
25 g	Estimated to ship onOctober 21, 2026fromMILWAUKEE	$261.00
100 g	Check Cart for Availability	$863.00

About This Item

Linear Formula:

ICH₂COONa

CAS Number:

305-53-3

Molecular Weight:

207.93

NACRES:

NA.77

PubChem Substance ID:

24895977

UNSPSC Code:

12352202

EC Number:

206-165-7

MDL number:

MFCD00002686

Beilstein/REAXYS Number:

4009322

$261.00

Estimated to ship onOctober 21, 2026Details

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

Sodium iodoacetate, ≥98%

biological source

synthetic (organic)

Quality Segment

200

assay

≥98%

form

powder

input

general use sample(s)

mp

208 °C (dec.) (lit.)

solubility

H₂O: 100 mg/mL

storage temp.

−20°C

SMILES string

[Na+].[O-]C(=O)CI

InChI

1S/C2H3IO2.Na/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1

InChI key

AGDSCTQQXMDDCV-UHFFFAOYSA-M

Description

Application

Reagent for the modification of cysteine residues in proteins.

Reagent for the modification of cysteine residues in proteins. Used in protein sequencing (including by Sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains.

Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease.

Biochem/physiol Actions

Used to induce osteoarthritis-like lesions and functional impairment in rats, for testing of chondroprotective agents and diagnostic imaging techniques.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	I9148	57858	242934
Sigma-Aldrich I2512 Sodium iodoacetate	Sigma-Aldrich I9148 Sodium iodoacetate	Sigma-Aldrich 57858 Sodium iodoacetate	Sigma-Aldrich 242934 Ethyl iodoacetate
description ≥98%	description BioUltra, ≥98%	description BioUltra, ≥99.5% (NT)	description 98%
assay ≥98%	assay ≥98%	assay ≥99.5% (NT)	assay 98%
biological source synthetic (organic)	biological source synthetic (organic)	biological source -	biological source -
Quality Level 200	Quality Level 200	Quality Level 100	Quality Level 200
form powder	form powder	form -	form -
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. 2-8°C
solubility H₂O: 100 mg/mL	solubility H₂O: 0.5 M, clear, colorless	solubility methanol: 0.1 M at 20 °C, clear, colorless	solubility -

Still not finding the right product?

Explore all of our products under Sodium iodoacetate

Pictograms

GHS06,GHS05

Signal Word

Danger

Hazard Codes

H301,H314

Precautionary Statements

P260 - P270 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point (°F)

406.4 °F

Flash Point (°C)

208 °C

PPE (personal protective equipment)

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.