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I4028

Monoclonal Anti-Interleukin-18 Receptor antibody produced in mouse

clone 70625.111, purified immunoglobulin, lyophilized powder

Synonym(s):

Anti-IL-18 Receptor

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Size/SKUAvailabilityPrice
0.5 mg

Available to ship TODAYfromMILWAUKEE

$918.00
$780.30

About This Item

UNSPSC Code:
51111800
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
70625.111, monoclonal
Application:
FACS, ICC, IHC
Citations:
2

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biological source

mouse

Quality Segment

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

70625.111, monoclonal

form

lyophilized powder

species reactivity

human

technique(s)

flow cytometry: suitable (2.5μg/SUP>106 cell), immunocytochemistry: 8-25 μg/mL, immunohistochemistry: 8-25 μg/mL

isotype

IgG1

UniProt accession no.

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... IL18R1(8809)

General description

The antibody will neutralize the biological activity of recombinant human IL-18 receptor.

Immunogen

recombinant human IL-18 receptor extracellular domain, expressed in NS0 cells.

Biochem/physiol Actions

IL-18 belongs to the IL-1 cytokine superfamily and is a regulator of innate and acquired immune responses. The immune responses of IL-18 are mediated by its interaction and subsequent signaling by IL-18 receptor complex. The IL-18R complex is made up of α chain that binds to extracellular IL-18 and a β chain that is involved in signal transduction. The IL-18/IL-18R signaling enhances T and NK cell maturation, cytotoxicity and secretion of cytokines.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Preparation Note

Purified using protein G.

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I3642I2519
description

clone 70625.111, purified immunoglobulin, lyophilized powder

description

clone 8516.311, purified immunoglobulin, lyophilized powder

description

clone 6217, purified immunoglobulin, lyophilized powder

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

species reactivity

human

species reactivity

human

species reactivity

human

Gene Information

human ... IL18R1(8809)

Gene Information

human ... IL1B(3553)

Gene Information

human ... IL8(3576)

biological source

mouse

biological source

mouse

biological source

mouse

clone

70625.111, monoclonal

clone

8516.311, monoclonal

clone

6217, monoclonal

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin


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Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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