Skip to Content
MilliporeSigma

Key Documents

View All Documentation

Skip To

I5529

IgG3, Lambda from human myeloma plasma

purified immunoglobulin, >90% (microfluidic capillary gel electrophoresis)

Synonym(s):

Human IgG3-λ

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
1 mg
Check Cart for Availability
$590.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
MFCD00163926
Conjugate:
unconjugated
Species reactivity:
-
Application:
—
Citations:
1

$590.00

Check Cart for Availability
​
Request a Custom Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

human

Quality Segment

conjugate

unconjugated

antibody form

purified immunoglobulin

assay

>90% (microfluidic capillary gel electrophoresis)

shipped in

dry ice

storage temp.

−20°C

General description

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections. IgG3 is the has a unique extended hinge region conferring greater flexibility
IgG3, λ from human myeloma plasma is purified by fractionation, ion-exchange and affinity chromatography.
Identity of IgG3, lambda light chain is verified by subclass monoclonal antibodies and type specific polyclonal antibodies in immunoelectrphoresis and indirect ELISA assays.
Mammalian immunoglobins contain either lambda or kappa light chains.

Application

IgG3, lambda light chain may be used as an antigen for the production and evaluation of antibodies developed for the indentification and classification of IgG3 subtypes. The purified IgG3, lambda may be used as an immunoglobulin calibrator, reference antigen, blocking agent or coating protein in a variety of immunoassays including ELISA, dot-blot immunobinding, Western immunoblotting, immunodiffusion, immunoelectrophoresis, hemagglutination, and cell-binding assays.
The purified IgG3, λ may be used as an immunoglobulin calibrator, reference antigen, blocking agent or coating protein in a variety of immunoassays including ELISA, dot-blot immunobinding, Western immunoblotting, immunodiffusion, immunoelectrophoresis, hemagglutination, and cell-binding assays.

Physical form

Solution in 20 mM tris buffered saline, pH 8.0.

Analysis Note

The purity and identity are determined by immunoelectrophoresis, indirect ELISA, and SDS-PAGE.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
I5029M9019I3784
IgG3, Lambda from human myeloma plasma purified immunoglobulin, >90% (microfluidic capillary gel electrophoresis)

Sigma-Aldrich

I5529

IgG3, Lambda from human myeloma plasma

IgG1, Lambda from human myeloma plasma purified immunoglobulin, >95% (SDS-PAGE)

Sigma-Aldrich

I5029

IgG1, Lambda from human myeloma plasma

IgG3, Lambda from murine myeloma clone Y5606, purified immunoglobulin, buffered aqueous solution

Sigma-Aldrich

M9019

IgG3, Lambda from murine myeloma

IgG3, Kappa from murine myeloma clone DX, purified immunoglobulin, buffered aqueous solution

Sigma-Aldrich

I3784

IgG3, Kappa from murine myeloma

description

purified immunoglobulin, >90% (microfluidic capillary gel electrophoresis)

description

purified immunoglobulin, >95% (SDS-PAGE)

description

clone Y5606, purified immunoglobulin, buffered aqueous solution

description

clone DX, purified immunoglobulin, buffered aqueous solution

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

biological source

human

biological source

human

biological source

mouse

biological source

mouse

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

assay

>90% (microfluidic capillary gel electrophoresis)

assay

>95% (SDS-PAGE)

assay

-

assay

≥95% (microfluidic capillary gel electrophoresis)

Storage Class

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Questions

Reviews

No rating value

Active Filters