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I5659

Idebenone

≥98% (HPLC), powder

Synonym(s):

2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione

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Size/SKUAvailabilityPrice
25 mg
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$186.00
100 mg
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$589.00

About This Item

Empirical Formula (Hill Notation):
C19H30O5
CAS Number:
Molecular Weight:
338.44
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.25
MDL number:

$186.00


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Product Name

Idebenone, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

powder

solubility

methanol: 50 mg/mL, clear to slightly hazy

storage temp.

room temp

SMILES string

O=C(C(OC)=C1OC)C(CCCCCCCCCCO)=C(C)C1=O

InChI

1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3

InChI key

JGPMMRGNQUBGND-UHFFFAOYSA-N

General description

Idebenone is a short-chain benzoquinone drug.

Application

Idebenone has been used:
  • to treat mutant myocilin (mMYOC) cells for drug treatment assay
  • to validate C2C12 secondary cell screening assay
  • to treat obese mice, to test whether idebenone and CoQ10 bind directly to peroxisome proliferator-activated receptor (PPAR)LBDs, His-tagged PPARα, δ and γ LBDs

Biochem/physiol Actions

A short-chain Coenzyme Q analog that enhances superoxide formation, presumably by mediating electron transfer from N2 to oxygen.
Idebenone is used in the treatment of visual impairment in adolescents and adults with Leber′s hereditary optic neuropathy (LHON). It serves as an antioxidant. It helps to guard the heart muscle against oxidative stress.

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This Item
67805PZ0006E1406
description

≥98% (HPLC)

description

analytical standard

description

≥98% (HPLC)

description

≥98% (HPLC), powder

assay

≥98% (HPLC)

assay

≥97.0% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

solubility

methanol: 50 mg/mL, clear to slightly hazy

solubility

-

solubility

DMSO: ≥20 mg/mL

solubility

DMSO: >10 mg/mL, H2O: insoluble

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

200

form

powder

form

-

form

powder

form

powder

storage temp.

room temp

storage temp.

-

storage temp.

2-8°C

storage temp.

-


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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