Skip to Content
MilliporeSigma

Skip To

I6410

ISCK03

≥98% (HPLC), solid

Promotion Available

Synonym(s):

Benzenesulfonamide,4-(1,1-dimethylethyl)-N-[4-(1H-imidazol-1-yl)phenyl], [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide

Sign In to View Organizational & Contract Pricing.

Spend $500 — Save 5%; Spend $750 — Save 10%; Spend $1,000 — Save 22%*

Sign in to check eligibility. Shop Products

Select a Size

Change View
Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$141.00
25 mg

Available to ship TODAYfromMILWAUKEE

$371.00

About This Item

Empirical Formula (Hill Notation):
C19H21N3O2S
CAS Number:
Molecular Weight:
355.45
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
solid

$141.00

Save Up To 22%


Available to ship TODAYDetails


​
Request a Custom Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


Quality Segment

assay

≥98% (HPLC)

form

solid

color

yellow

solubility

DMSO: ≥20 mg/mL, H2O: insoluble

storage temp.

2-8°C

SMILES string

CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)-n3ccnc3

InChI

1S/C19H21N3O2S/c1-19(2,3)15-4-10-18(11-5-15)25(23,24)21-16-6-8-17(9-7-16)22-13-12-20-14-22/h4-14,21H,1-3H3

InChI key

XQABBHBFHWHMKF-UHFFFAOYSA-N

Biochem/physiol Actions

ISCK03 inhibits in vitro phosphorylation of c-Kit in a dose dependent manner.
ISCK03 inhibits in vitro phosphorylation of c-Kit in a dose dependent manner. ISCK03 inhibits SCF (stem cell factor)-induced c-kit phosphorylation in 501mel human melanoma cells. Complete inhibition was observed with 1 and 5 μM ISCK03.

Features and Benefits

This compound is featured on the PDGFR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
SML1276SML1855SML0187
description

≥98% (HPLC), solid

description

≥98% (HPLC)

description

≥97% (HPLC)

description

≥98% (HPLC)

form

solid

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥97% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: ≥20 mg/mL, H2O: insoluble

solubility

DMSO: 10 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: ≥10 mg/mL

color

yellow

color

white to beige

color

yellow to orange

color

white to tan


Storage Class

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library




Questions

Reviews

No rating value

Active Filters