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I8026

Anti-Interleukin-8 antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-CXCL8, Anti-IL-8

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0.1 mg
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$649.00
$551.65

About This Item

UNSPSC Code:
51111800
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ICC, IHC, Neutral, WB
Citations:
6

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biological source

goat

Quality Segment

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human

technique(s)

immunocytochemistry: 5-15 μg/mL, immunohistochemistry: 5-15 μg/mL, neutralization: suitable, western blot: 0.1 μg/mL

storage temp.

−20°C

Gene Information

human ... IL8(3576)

General description

Interleukin 8 (IL-8) is an 8kD, 72 amino acid residue containing cytokine that belongs to C-X-C chemokine family . The IL-8 gene is mapped to human chromosome 4q13.3.

Immunogen

recombinant human IL-8 (CXCL8).

Application

Anti-Interleukin-8 antibody can be used for the following :
  • For neutralizing the biological activity of recombinant human IL-8 and natural human IL-8.
  • Immunoblotting.
  • ELISA.
Anti-Interleukin-8 antibody can be used in immunocytochemistry and immunohistochemistry.

Biochem/physiol Actions

Interleukin 8 (IL-8) stimulates neutrophils to produce lysosomal enzymes along with myeloperoxidase, α-mannosidase and β-glucuronidase . Goat anti-Interleukin-8 antibody reacts specifically with recombinant and natural human IL-8 but not with recombinant human GROα. Elevated expression of the gene is observed in a number of cancers including chronic spontaneous urticaria and breast cancer, thus serves as a prognostic marker for the same. IL-8 regulates the metastasis and angiogenesis processes during cancer development. IL-8 is responsible for epithelial–mesenchymal transition which plays an important role in providing cancer cells the mobility to invade other neighbouring cells, thereby contributing to metastasis.
The antibody will neutralize the biological activity of recombinant and natural human IL-8, but not recombinant human GROα.

Physical form

Lyophilized from 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Quality Level

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Quality Level

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Quality Level

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Quality Level

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conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

biological source

goat

biological source

mouse

biological source

mouse

biological source

rabbit

antibody form

affinity isolated antibody

antibody form

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antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

clone

polyclonal

clone

6217, monoclonal

clone

6G4, monoclonal

clone

polyclonal


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Storage Class

13 - Non Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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