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I8409

Anti-Interleukin-7 Receptor α/CD127 antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-CD127, Anti-CDW127, Anti-IL7R, Anti-ILRA

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Size/SKUAvailabilityPrice
100 μg

Available to ship TODAYfromMILWAUKEE

$686.00
$583.10

About This Item

UNSPSC Code:
51111800
NACRES:
NA.41
MDL number:
MFCD01864808
Conjugate:
unconjugated
Clone:
polyclonal
Application:
FACS, WB
Citations:
7

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biological source

goat

Quality Segment

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human

technique(s)

flow cytometry: 5.0-10.0 μg/mL, western blot: 0.1-0.2 μg/mL

UniProt accession no.

P16871

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... IL7R(3575)

General description

Interleukin-7 (IL-7) is a stromal-cell derived cytokine that is important in the development of adaptive immunity and maintenance of T cells and B cells. The cognate receptor that binds IL-7 is the IL-7 receptor complex, made up of IL-7 R α chain and a γ chain. The expression of IL-7 R is restricted to immature B cells, mature T cells and thymocytes. The binding of IL-7 to its receptor triggers a variety of tightly regulated signalling pathways that are critical for cell survival, proliferation, differentiation and uptake of glucose. The signalling pathways that participate in mediating the effects of IL-7 R are JAK/STAT and PI3K. Additionally the effect of IL-7 on cell cycle is due to the modulation of proteins p27kip1 and Cdc25A. Reports implicate IL-7 R in glucose metabolism and cell size as it modulates the effects of GLUT4
Anti-interleukin-7 receptor α/CD127 recognizes human interleukin-7.
Interleukin-7 Receptor α/CD127 encodes a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including

Immunogen

purified, NSO cell-derived recombinant human interleukin-7 soluble receptor α.

Application

Anti-interleukin-7 receptor α/CD127 antibody may be used for immunoblotting at a working concentration of 0.1-0.2 μg/ml. For flow cytometry, the recommended concentration is 5-10 μg/ml.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Anti-Interleukin-7 Receptor α/CD127 antibody produced in goat affinity isolated antibody, lyophilized powder

Sigma-Aldrich

I8409

Anti-Interleukin-7 Receptor α/CD127 antibody produced in goat

Anti-IL-7R antibody produced in rabbit affinity isolated antibody

Sigma-Aldrich

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Anti-Interleukin-7/IL-7 Antibody, clone 7B1.1 clone 7B1.1, from mouse

Sigma-Aldrich

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Anti-Interleukin-2 antibody produced in goat IgG fraction of antiserum, lyophilized powder

Sigma-Aldrich

I8273

Anti-Interleukin-2 antibody produced in goat

description

affinity isolated antibody, lyophilized powder

description

affinity isolated antibody

description

clone 7B1.1, from mouse

description

IgG fraction of antiserum, lyophilized powder

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

biological source

goat

biological source

rabbit

biological source

mouse

biological source

goat

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

antibody form

IgG fraction of antiserum

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

Gene Information

human ... IL7R(3575)

Gene Information

human ... IL7RA(3575)

Gene Information

human ... IL7(3574)

Gene Information

human ... IL2(3558)

form

lyophilized powder

form

buffered aqueous solution

form

-

form

lyophilized powder

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Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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