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Monoclonal Anti-Intracellular Adhesion Molecule 3 antibody produced in mouse

Name: Monoclonal Anti-Intracellular Adhesion Molecule 3 antibody produced in mouse
Brand: SIGMA
Price: 692 USD
Availability: InStock

~1 mg/mL, clone 186-2G9, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-ICAM-3

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Size/SKU	Availability	Price
100 μg	Check Cart for Availability	$692.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD01094485

Conjugate:

unconjugated

Clone:

186-2G9, monoclonal

Application:

FACS, IF (d), IHC, IP, WB

Citations:

$692.00

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Properties

Quality Segment

200

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

186-2G9, monoclonal

form

buffered aqueous solution

mol wt

antigen 120 kDa

species reactivity

human

concentration

~1 mg/mL

technique(s)

direct immunofluorescence: 2 μg using 1 mg protein lysate, flow cytometry: 2 μg using 1 mg protein lysate, immunohistochemistry: 2-4 μg/mL using human tonsil tissue sections, immunoprecipitation (IP): 2 μg using 1 mg protein lysate, western blot: 1-5 μg/mL

UniProt accession no.

P32942

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ICAM3(3385)

Description

General description

The gene ICAM3 (intercellular adhesion molecule 3) encodes type I membrane glycoprotein that belongs to the immunoglobulin (ig) superfamily. The encoded protein is extensively glycosylated and contains five Ig-like domains that share high homology with corresponding domains in ICAM-1 and ICAM-2. ICAM3 is found to be expressed on all leukocytes, including the resting leukocytes. The gene is mapped to human chromosome 19p13.2.

Immunogen

stimulated human leukocytes.

Biochem/physiol Actions

The protein intercellular adhesion molecule 3 (ICAM-3) functions as a receptor for LFA-1 (leukocyte function-associated antigen-1) and mediates adhesive interactions of leukocyte cell surface adhesion molecules in inflammatory and immune response. LFA-1 participates in several processes, such as T cell-mediated killing, T helper and B lymphocyte responses, natural killing, Ab-dependent cellular cytotoxicity by monocytes and granulocytes, and adherence of leukocytes to endothelial cells, fibroblasts, and epithelial cells. ICAM-3 mediates the adhesion of resting T lymphocytes to LFA-1 and participates in the initiation of immune responses. It may also function in lymphocyte activation, as well as in adhesion.

Physical form

Solution in phosphate buffered saline pH 7.4, containing 0.08% sodium azide.

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This Item	SAB4700337	M5815	H6411
Sigma-Aldrich I9031 Monoclonal Anti-Intracellular Adhesion Molecule 3 antibody produced in mouse	Sigma-Aldrich SAB4700337 Monoclonal Anti-CD50-Biotin antibody produced in mouse	Sigma-Aldrich M5815 Monoclonal Anti-Myogenin antibody produced in mouse	Sigma-Aldrich H6411 Monoclonal Anti-HIF-1α antibody produced in mouse
description ~1 mg/mL, clone 186-2G9, purified immunoglobulin, buffered aqueous solution	description clone MEM-171, purified immunoglobulin, buffered aqueous solution	description clone F12B, purified immunoglobulin, buffered aqueous solution	description ~1 mg/mL, clone OZ12, purified immunoglobulin, buffered aqueous solution
antibody form purified immunoglobulin	antibody form purified immunoglobulin	antibody form purified immunoglobulin	antibody form purified immunoglobulin
biological source mouse	biological source mouse	biological source mouse	biological source mouse
clone 186-2G9, monoclonal	clone MEM-171, monoclonal	clone F12B, monoclonal	clone OZ12, monoclonal
Gene Information human ... ICAM3(3385)	Gene Information human ... ICAM3(3385)	Gene Information human ... MYOG(4656) mouse ... Myog(17928) rat ... Myog(29148)	Gene Information human ... HIF1A(3091)
species reactivity human	species reactivity human	species reactivity mouse, rat, human	species reactivity human
conjugate unconjugated	conjugate biotin conjugate	conjugate unconjugated	conjugate unconjugated

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Storage Class

10 - Combustible liquids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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