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K3268

PAK7, active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):

KIAA1264, MGC26232, PAK5

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Size/SKUAvailabilityPrice
10 μg
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$432.00

About This Item

NACRES:
NA.32
UNSPSC Code:
51111800
Specific activity:
47-63 nmol/min·mg
Assay:
≥70% (SDS-PAGE)
Recombinant:
expressed in baculovirus infected Sf9 cells

$432.00


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recombinant

expressed in baculovirus infected Sf9 cells

Quality Segment

product line

PRECISIO® Kinase

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

47-63 nmol/min·mg

mol wt

~130 kDa

UniProt accession no.

relevant disease(s)

cancer

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... PAK7(57144)

Biochem/physiol Actions

PAK7 (p21 protein (Cdc42/Rac)-activated kinase 7) belongs to the group-2 PAKs and can activate JNK (Jun N-terminus kinase). It contain an amino-terminal CDC42 (cell division cycle 42)/RAC (AKT1, v-akt murine thymoma viral oncogene homolog 1) interactive domain and a carboxyl terminal kinase domain. It plays an important role in outgrowth of neuron cells and synaptic vesicle trafficking. In mice, absence of PAK7 and PAK6 causes learning and locomotion defects. It is mainly expressed in brain. However, it is also considered as an oncogene because of its expression in colorectal, esophageal and gastric cancers.

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

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description

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

description

≥75% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution

description

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

description

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

specific activity

47-63 nmol/min·mg

specific activity

10 units/mg protein (Bradford)

specific activity

-

specific activity

116-158 nmol/min·mg

assay

≥70% (SDS-PAGE)

assay

≥75% (SDS-PAGE)

assay

-

assay

≥70% (SDS-PAGE)

Gene Information

human ... PAK7(57144)

Gene Information

human ... PAK7(57144)

Gene Information

human ... PAK7(57144)

Gene Information

human ... PAK6(56924)

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in E. coli

recombinant

-

recombinant

expressed in baculovirus infected Sf9 cells

storage temp.

−70°C

storage temp.

−70°C

storage temp.

−20°C

storage temp.

−70°C


Storage Class

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)



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