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K3519

KRM-III

≥98% (HPLC)

Synonym(s):

1,3-Dihydro-1,4-diphenyl-2H-imidazole-2-thione

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Size/SKUAvailabilityPrice
5 mg
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$117.00
25 mg
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$659.00

About This Item

Empirical Formula (Hill Notation):
C15H12N2S
CAS Number:
Molecular Weight:
252.33
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$117.00


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

light yellow to light tan

solubility

DMSO: soluble ≥20 mg/mL

storage temp.

2-8°C

SMILES string

S=C1NC(=CN1c2ccccc2)c3ccccc3

InChI

1S/C15H12N2S/c18-15-16-14(12-7-3-1-4-8-12)11-17(15)13-9-5-2-6-10-13/h1-11H,(H,16,18)

InChI key

QKOAQVKXZJFMET-UHFFFAOYSA-N

Biochem/physiol Actions

KRM-III is an inhibitor of T cell antigen receptor (TCR), an inhibitor of phorbol myristate acetate (PMA) /ionomycin-induced nuclear factor of activated T cells (NFAT) activation and T cell proliferation.

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This Item
524400P14879346
description

≥98% (HPLC)

description

Phorbol-12-myristate-13-acetate, CAS 16561-29-8, is the most common phorbol ester. Activates PKC at nanomolar concentrations.

description

solid, ≥95% (TLC)

description

synthetic, ≥98.0% (TLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥95% (TLC)

assay

≥98.0% (TLC)

form

powder

form

solid

form

solid

form

film, powder or solid (or crystals)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

solubility

DMSO: soluble ≥20 mg/mL

solubility

DMSO: 10 mg/mL

solubility

ethanol: soluble, DMSO: soluble, H2O: ~2 μM

solubility

chloroform: 10 mg/mL, clear, colorless to light yellow

color

light yellow to light tan

color

white

color

white

color

white


Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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