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L0664

Loxoprofen

solid

Synonym(s):

α-Methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic acid, Koloxo

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Pack SizeSKUAvailabilityPrice
5 mg
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$425.00
$361.25

About This Item

Empirical Formula (Hill Notation):
C15H18O3
CAS Number:
68767-14-6
Molecular Weight:
246.30
NACRES:
NA.77
PubChem Substance ID:
24278509
UNSPSC Code:
12352200
MDL number:
MFCD00864331
Form:
solid
Quality level:
200

$361.25

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form

solid

Quality Level

200

originator

Daiichi-Sankyo

SMILES string

CC(C(O)=O)c1ccc(CC2CCCC2=O)cc1

InChI

1S/C15H18O3/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16/h5-8,10,13H,2-4,9H2,1H3,(H,17,18)

InChI key

YMBXTVYHTMGZDW-UHFFFAOYSA-N

Gene Information

human ... PTGS1(5742), PTGS2(5743)

Application

Anti-inflammatory; analgesic

Features and Benefits

This compound was developed by Daiichi-Sankyo. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Show Differences

1 of 1

This Item
SML1452I4883M196
Loxoprofen solid

Sigma-Aldrich

L0664

Loxoprofen

Ibufenac ≥95% (HPLC)

Sigma-Aldrich

SML1452

Ibufenac

Ibuprofen ≥98% (GC)

Sigma-Aldrich

I4883

Ibuprofen

(+)-α-Methyl-4-carboxyphenylglycine solid

Sigma-Aldrich

M196

(+)-α-Methyl-4-carboxyphenylglycine

form

solid

form

powder

form

powder

form

solid

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

200

originator

Daiichi-Sankyo

originator

-

originator

-

originator

-

Gene Information

human ... PTGS1(5742), PTGS2(5743)

Gene Information

human ... PTGS1(5742), PTGS2(5743)

Gene Information

human ... ALB(213), ALOX5(240), CYP1A2(1544), CYP2C9(1559), IL8RA(3577), PTGS1(5742), PTGS2(5743)
mouse ... Alox5(11689)
rat ... Alox5(25290), Ptgs1(24693)

Gene Information

rat ... Grm1(24414)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
101K1463

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Articles

Discover Bioactive Small Molecules for Lipid Signaling Research

Discover Bioactive Small Molecules for Lipid Signaling Research

Yasushi Kuribayashi et al.
The journal of obstetrics and gynaecology research, 43(9), 1465-1471 (2017-07-15)
We aimed to determine the frequency of endometrial cancer in infertile women undergoing hysteroscopic endometrial polypectomy for endometrial polyps. A total of 1035 infertile patients who underwent office-based hysteroscopic polypectomy at Sugiyama Clinic Marunouchi between July 2011 and October 2015
M Sugimoto et al.
Biochemical pharmacology, 42(12), 2363-2368 (1991-11-27)
The effect of loxoprofen-Na, a novel non-steroidal anti-inflammatory drug with a prodrug property, on prostaglandin (PG) levels in the inflammatory tissue was investigated with a carrageenin-induced pleurisy model in rats. The intrapleural injection of carrageenin caused a marked increase in
Misato Hashizume et al.
Modern rheumatology, 20(5), 432-438 (2010-04-22)
We examined the therapeutic effect of high molecular weight hyaluronic acid (HA) on the progression of joint pain and cartilage degeneration in a rabbit osteoarthritis (OA) model. The OA model was induced by partial meniscectomy. In the time course study
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Global Trade Item Number

SKUGTIN
L0664-5MG04061832785561

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