L1045
LY-354740 hydrate
≥98% (HPLC)
Synonym(s):
(1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxy lic acid, Eglumegad, Eglumetad, LY-354740
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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Available to ship TODAY | $167.00 |
About This Item
Empirical Formula (Hill Notation):
C8H11NO4 · xH2O
Molecular Weight:
185.18 (anhydrous basis)
UNSPSC Code:
12352209
NACRES:
NA.77
eCl@ss:
32160406
Assay:
≥98% (HPLC)
Form:
solid
$167.00
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Quality Segment
assay
≥98% (HPLC)
form
solid
solubility
deionized water: 8 mg/mL
originator
Eli Lilly
storage temp.
room temp
Application
LY-354740 hydrate has been used as a metabotropic glutamate receptor group II/III agonist to study its behavioral effectsof electric shock on Gammarus fossarum.
Biochem/physiol Actions
LY-354740 is a highly selective and potent agonist of group II mGlu (metabotropic glutamate) receptors.
LY-354740 is a highly selective and potent agonist of group II mGlu (metabotropic glutamate) receptors. It displays antianxiety and antiaddictive activity in vivo. It?s orally and systemically active. It is anxiolytic and inhibits symptoms of morphine withdrawal in morphine-dependent mice.
Features and Benefits
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form solid | form solid | form powder | form powder |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. room temp | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. room temp |
| solubility deionized water: 8 mg/mL | solubility deionized water: >10 mg/mL | solubility H2O: 2 mg/mL, clear (warmed) | solubility H2O: 20 mg/mL, clear |
| originator Eli Lilly | originator - | originator - | originator - |
Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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