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L1898

[D-Ala6]-LH-RH acetate salt hydrate

≥97% (HPLC), LH-RH agonist

Synonym(s):

(D-Ala-6) Luteinizing Hormone Releasing Hormone

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$616.00

About This Item

Empirical Formula (Hill Notation):
C56H77N17O13 · xC2H4O2 · yH2O
Molecular Weight:
1196.32 (anhydrous free base basis)
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.77

$616.00


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Product Name

[D-Ala6]-LH-RH acetate salt hydrate, ≥97% (HPLC)

Quality Segment

assay

≥97% (HPLC)

composition

Peptide content, ≥65%

UniProt accession no.

storage temp.

−20°C

SMILES string

[H]O[H].CC(O)=O.CC(C)C[C@H](NC(=O)[C@@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc4cnc[nH]4)NC(=O)[C@@H]5CCC(=O)N5)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N6CCC[C@H]6C(=O)NCC(N)=O

InChI

1S/C56H77N17O13.C2H4O2.H2O/c1-29(2)20-39(50(81)67-38(10-6-18-61-56(58)59)55(86)73-19-7-11-44(73)54(85)63-26-45(57)76)68-47(78)30(3)65-49(80)40(21-31-12-14-34(75)15-13-31)69-53(84)43(27-74)72-51(82)41(22-32-24-62-36-9-5-4-8-35(32)36)70-52(83)42(23-33-25-60-28-64-33)71-48(79)37-16-17-46(77)66-37;1-2(3)4;/h4-5,8-9,12-15,24-25,28-30,37-44,62,74-75H,6-7,10-11,16-23,26-27H2,1-3H3,(H2,57,76)(H,60,64)(H,63,85)(H,65,80)(H,66,77)(H,67,81)(H,68,78)(H,69,84)(H,70,83)(H,71,79)(H,72,82)(H4,58,59,61);1H3,(H,3,4);1H2/t30-,37+,38+,39+,40+,41+,42+,43+,44+;;/m1../s1

InChI key

KGUIXKYKIZMKMT-JGUOWLKQSA-N

Gene Information

human ... GNRH1(2796)

Application

[D-Ala6]-LH-RH acetate salt hydrate has been used to induce ovulation and to synchronize the reproductive cycle in Sprague-Dawley female rats.

Biochem/physiol Actions

(D-Ala6)-LH-RH is a GnRH (gonadotropin-releasing hormone) agonist. GnRH, which is also referred to as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism.
Potent LH-RH agonist.

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This Item
L9761L7134L4897
description

≥97% (HPLC)

description

≥97% (HPLC), powder

description

≥98% (HPLC), powder

description

≥97% (HPLC)

assay

≥97% (HPLC)

assay

≥97% (HPLC)

assay

≥98% (HPLC)

assay

≥97% (HPLC)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

Gene Information

human ... GNRH1(2796)

Gene Information

human ... GNRH1(2796), GNRHR(2798)

Gene Information

human ... GNRH1(2796)

Gene Information

human ... GNRH1(2796), GNRHR(2798)
mouse ... GNRH1(14714), GNRHR(14715)
rat ... GNRH1(25194), GNRHR(81668)

UniProt accession no.

P01148

UniProt accession no.

P01148, P30968

UniProt accession no.

P01148

UniProt accession no.

P01148, P07490, P13562, P30968, P55248, Q01776, P30969

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

composition

Peptide content, ≥65%

composition

-

composition

-

composition

-


Pictograms

Health hazard

Signal Word

Danger

Hazard Codes

Precautionary Statements

Hazard Classifications

Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges



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