L2545
LY225910
≥98% (HPLC)
Synonym(s):
2-[2-(5-Bromo-1H-indol-3-yl)ethyl]-3-[3-(1-methylethoxy )phenyl]-4-(3H)-quinazolinone
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
25 mg | Check Cart for Availability | $366.00 |
About This Item
Quality Segment
assay
≥98% (HPLC)
form
powder
color
off-white
solubility
DMSO: >20 mg/mL
originator
Eli Lilly
storage temp.
2-8°C
SMILES string
CC(C)Oc1cccc(c1)N2C(CCc3c[nH]c4ccc(Br)cc34)=Nc5ccccc5C2=O
InChI
1S/C27H24BrN3O2/c1-17(2)33-21-7-5-6-20(15-21)31-26(30-25-9-4-3-8-22(25)27(31)32)13-10-18-16-29-24-12-11-19(28)14-23(18)24/h3-9,11-12,14-17,29H,10,13H2,1-2H3
InChI key
KUECXUACQOYKNB-UHFFFAOYSA-N
Biochem/physiol Actions
LY225910 is a potent, selective CCK2 antagonist. LY225910 blocks agonism of CCK2 by CCK-8S, the peptide agonist. LY225910 has been measured in multiple systems, including GABA efflux from cortical cultures, depolarization of spinal cord neurons (via potassium conductance), modulation of excitatory postsynaptic potentials (EPSPs) in nucleus accumbens slices, and enhancement of morphine analgesia.
Features and Benefits
1 of 1
This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC), powder | description ≥98% (HPLC) | description ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. room temp |
| solubility DMSO: >20 mg/mL | solubility DMSO: ≥20 mg/mL | solubility DMSO: >20 mg/mL | solubility H2O: >10 mg/mL |
| color off-white | color white to tan | color off-white to light brown | color white to off-white |
Signal Word
Danger
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Chronic 4
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
638.6 - 762.1 °F
Flash Point (°C)
337 - 405.6 °C
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