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L4129

L-α-Lysophosphatidylcholine from egg yolk

≥99%, Type I, powder

Synonym(s):

1-Acyl-sn-glycero-3-phosphocholine, L-α-Lysolecithin

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Size/SKUAvailabilityPrice
25 mg

Estimated to ship onSeptember 08, 2026fromMILWAUKEE

$73.10
100 mg

Estimated to ship onSeptember 08, 2026fromMILWAUKEE

$214.00
500 mg

Estimated to ship onSeptember 08, 2026fromMILWAUKEE

$646.00
1 g

Estimated to ship onSeptember 08, 2026fromMILWAUKEE

$1,170.00

About This Item

CAS Number:
UNSPSC Code:
12352211
EC Number:
232-715-0
NACRES:
NA.25
MDL number:

$73.10


Estimated to ship onSeptember 08, 2026Details


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biological source

egg yolk

Quality Segment

description

zwitterionic

type

Type I

assay

≥99%

form

powder

color

white

functional group

phospholipid

lipid type

phosphoglycerides

shipped in

ambient

storage temp.

−20°C

Application

L-α-Lysophosphatidylcholine from egg yolk has been used:
  • as a surfactant
  • as a media supplement and in Staphylococcus aureus inhibition assay in dermatitis
  • as a demyelinating agent for nerve
  • as a component in sperm nuclei preparation buffer

Biochem/physiol Actions

Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun.
Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun. Lysophosphatidylcholine accumulates during cardiac ischemia and may induce arrhythmias by uncoupling gap junction communication, and increase ischemic damage by enhancing Na+ loading in cardiac myocytes. It also activates TREK1, TREK2 and TRAAK K+ channels.

Preparation Note

Prepared by the action of phospholipase A on egg L-α-phosphatidylcholine.

Analysis Note

Contains primarily palmitic and stearic acids.

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P2772L4754L0906
description

≥99%, Type I, powder

description

egg yolk, Type XI-E, 100 mg/mL in chloroform, ≥99%, solution

description

Type I, ≥99%

description

≥99%, lyophilized powder

assay

≥99%

assay

≥99%

assay

≥99%

assay

≥99%

form

powder

form

solution

form

powder

form

lyophilized powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

biological source

egg yolk

biological source

egg yolk

biological source

egg yolk

biological source

soybean

description

zwitterionic

description

-

description

-

description

zwitterionic

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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