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L9668

Lidoflazine

≥98% (HPLC), powder

Synonym(s):

4-[4,4-Bis(4-fluorophenyl)butyl]-N-(2,6-dimethylphenyl)-1-piperazineacetamide

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Size/SKUAvailabilityPrice
5 mg
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$182.00

About This Item

Empirical Formula (Hill Notation):
C30H35F2N3O
CAS Number:
3416-26-0
Molecular Weight:
491.62
NACRES:
NA.77
PubChem Substance ID:
329817673
UNSPSC Code:
12352200
EC Number:
222-312-8
MDL number:
MFCD00057353
Assay:
≥98% (HPLC)
Form:
powder

$182.00

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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white

solubility

DMSO: ≥10 mg/mL

storage temp.

2-8°C

SMILES string

Cc1cccc(C)c1NC(=O)CN2CCN(CCCC(c3ccc(F)cc3)c4ccc(F)cc4)CC2

InChI

1S/C30H35F2N3O/c1-22-5-3-6-23(2)30(22)33-29(36)21-35-19-17-34(18-20-35)16-4-7-28(24-8-12-26(31)13-9-24)25-10-14-27(32)15-11-25/h3,5-6,8-15,28H,4,7,16-21H2,1-2H3,(H,33,36)

InChI key

ZBIAKUMOEKILTF-UHFFFAOYSA-N

Biochem/physiol Actions

HERG calcium channel blocker
Lidoflazine is an antianginal calcium channel blocker that carries a significant risk of QT interval prolongation and ventricular arrhythmia. It prolongs QT interval by blocking HERG channel. IC50 < 0.1 μM

Features and Benefits

This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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This Item
AABH9ABBC778CIAH987F4B0AAMBH2D700F49
Lidoflazine &#8805;98% (HPLC), powder

Sigma-Aldrich

L9668

Lidoflazine

2-{4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl}-N-(2,6-dimethylphenyl)acetamide

AA BLOCKS, INC.

AABH9ABBC778

2-{4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl}-N-(2,6-dimethylphenyl)acetamide

4-Iodofluorobenzene

ChemScene LLC (Preferred Partner)

CIAH987F4B0A

4-Iodofluorobenzene

2-Iodo-9H-fluorene

Ambeed, Inc.

AMBH2D700F49

2-Iodo-9H-fluorene

description

≥98% (HPLC), powder

description

-

description

-

description

-

form

powder

form

-

form

-

form

-

assay

≥98% (HPLC)

assay

-

assay

-

assay

-

Quality Level

100

Quality Level

-

Quality Level

-

Quality Level

-

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

-

solubility

DMSO: ≥10 mg/mL

solubility

-

solubility

-

solubility

-

color

white

color

-

color

-

color

-

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves

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