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M216

MDL 105,519

≥98% (HPLC), NMDA receptor antagonist, solid

Synonym(s):

(E)-4,6-Dichloro-3-(2-phenyl-2-carboxyethenyl)indole-2-carboxylic acid

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5 mg

Available to ship TODAY

$737.00
$764.00
25 mg

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$2,960.00

About This Item

Empirical Formula (Hill Notation):
C18H11Cl2NO4
CAS Number:
Molecular Weight:
376.19
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.32
MDL number:

$764.00

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Product Name

MDL 105,519, ≥98% (HPLC), solid

Quality Segment

assay

≥98% (HPLC)

form

solid

color

white to off-white

solubility

DMSO: >20 mg/mL

SMILES string

OC(=O)C(=C/c1c([nH]c2cc(Cl)cc(Cl)c12)C(O)=O)\c3ccccc3

InChI

1S/C18H11Cl2NO4/c19-10-6-13(20)15-12(16(18(24)25)21-14(15)7-10)8-11(17(22)23)9-4-2-1-3-5-9/h1-8,21H,(H,22,23)(H,24,25)/b11-8-

InChI key

LPWVUDLZUVBQGP-FLIBITNWSA-N

Gene Information

human ... GRIN1(2902)
rat ... Grin1(24408)

Biochem/physiol Actions

MDL 105,519 is a high affinity N-methyl-D-aspartate (NMDA) glutamate receptor antagonist at the glycine site. It inhibits NMDA-dependent responses.

Legal Information

Sold under exclusive license from Hoechst Marion Roussel, Inc.

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description

≥98% (HPLC), solid

description

affinity isolated antibody, buffered aqueous solution

description

from rabbit, purified by affinity chromatography

description

clone 54.1, Chemicon®, from mouse

assay

≥98% (HPLC)

assay

-

assay

-

assay

-

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

100

form

solid

form

buffered aqueous solution

form

-

form

-

Gene Information

human ... GRIN1(2902)
rat ... Grin1(24408)

Gene Information

human ... GRIN1(2902)

Gene Information

human ... GRIN1(2902)
mouse ... Grin1(14810)
rat ... Grin1(24408)

Gene Information

frog ... Grin1(780048)
human ... GRIN1(2902)
rat ... Grin1(24408)
rhesus monkey ... Grin1(574380)

color

white to off-white

color

-

color

-

color

-

solubility

DMSO: >20 mg/mL

solubility

-

solubility

-

solubility

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



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