MSP12
Membrane Scaffold Protein 2N2
recombinant, expressed in E. coli, MSP1D1-MSP1D2 fusion protein
Sinonimo/i:
Membrane scaffold protein
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| A voi/SKU | Disponibilità | Prezzo |
|---|---|---|
5 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 493.00 |
Informazioni su questo articolo
recombinant
expressed in E. coli
Quality Segment
assay
≥90% (SDS-GE)
form
buffered aqueous solution
mol wt
45,541.2 Da
solubility
water: soluble
shipped in
ambient
storage temp.
−20°C
General description
The first MSP, MSP1, was engineered with its sequence based on the sequence of A-1 but without the globular N-terminal domain of native A-1. The Membrane Scaffold Protein 1D1 (MSP1D1) variant of MSP1 deletes the first 11 amino acids in the Helix 1 portion (referred to as “H0.5” in the accompanying figure) of the original MSP1 sequence. Membrane Scaffold Protein 2N2 (MSP 2N2) is a fusion of MSP1D1 and another MSP variant, MSP1D2. MSP1D2 deletes the first 22 amino acids of the original MSP sequence (i.e. the entire H1 segment). In MSP2N2, a GT linker connects MSP1D1 and MSP1D2.
Nanodisc technology is an approach rendering membrane proteins soluble in aqueous solutions in a native-like bilayer environment, where the membrane proteins remain stable and active. The Nanodisc concept is derived from high-density lipoprotein (HDL) particles and their primary protein component, apolipoprotein. The Nanodisc is a non-covalent structure of phospholipid bilayer and membrane scaffold protein (MSP), a genetically engineered protein that mimics the function of Apolipoprotein A-1 (ApoA-1).
Application
Biochem/physiol Actions
Legal Information
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Questo articolo | |||
|---|---|---|---|
| description recombinant, expressed in E. coli, MSP1D1-MSP1D2 fusion protein | description recombinant, expressed in E. coli, Cysteine substituted at position 73 | description recombinant, expressed in E. coli, Cysteine substituted at position 73 | description recombinant, expressed in E. coli, Cysteine substituted at position 73 |
| recombinant expressed in E. coli | recombinant expressed in E. coli | recombinant expressed in E. coli | recombinant expressed in E. coli |
| assay ≥90% (SDS-GE) | assay ≥90% (SDS-GE) | assay ≥90% (SDS-GE) | assay ≥90% (SDS-GE) |
| form buffered aqueous solution | form buffered aqueous solution | form buffered aqueous solution | form buffered aqueous solution |
| mol wt 45,541.2 Da | mol wt - | mol wt - | mol wt - |
| shipped in ambient | shipped in ambient | shipped in ambient | shipped in ambient |
| solubility water: soluble | solubility - | solubility - | solubility - |
Classe di stoccaggio
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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