Skip to Content
MilliporeSigma

Key Documents

View All Documentation

Skip To

MSST0004

SILu™Lite PTX3 Pentraxin-related protein 3 human

recombinant, expressed in HEK 293 cells, MS Protein Standard

Synonym(s):

SILuLite Pentraxin-related protein

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
50 μg

Estimated to ship onSeptember 29, 2026fromMILWAUKEE

$836.00

About This Item

NACRES:
NA.12
UNSPSC Code:
23201100
Form:
lyophilized powder
Assay:
≥98% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in HEK 293 cells

$836.00

Estimated to ship onSeptember 29, 2026Details

​
Request a Custom Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

human

Quality Segment

200

recombinant

expressed in HEK 293 cells

assay

≥98% (SDS-PAGE)

form

lyophilized powder

technique(s)

mass spectrometry (MS): suitable

UniProt accession no.

P26022

storage temp.

−20°C

Gene Information

human ... PTX3(5806)

General description

SILu™ Lite PTX3 is a recombinant glycosylated human protein expressed in human 293 cells. It is a homooctamer and a homodecamer consisting of 364 amino acids (monomer)with a calculated molecular weight of 40 kDa. It contains no tags.

Biochem/physiol Actions

Pentraxin 3 (PTX3) is a secreted glycosylated protein belonging to the pentraxin superfamily1. PTX3 is rapidly produced and released by several cell types, in particular by mononuclear phagocytes, dendritic cells (DCs), fibroblasts and endothelial cells in response to primary inflammatory signals (e.g., toll-like receptor [TLR]engagement,TNFα, IL-1β)1. PTX3 behaves as an acute phase response protein, as the blood levels of PTX3, low in normal conditions (about 25 ng/mL in the mouse, < 2 ng/mL in humans), increase rapidly (peaking at 6–8 h after induction) and dramatically (200–800 ng/mL)during endotoxic shock, sepsis and other inflammatory and infectious conditions, correlating with the severity of the disease. Under these conditions, PTX3 is a rapid marker for primary local activation of innate immunity and inflammation2−6. anti-apoptotic cell survival2, cell cycle regulation3, cell adhesion4, tissue remodeling5 and lipid transportation6. PTX3 gene expression in human endothelial cells is suppressed to a greater extent by pitavastatin than the expression of 6,000 other human genes that have been examined, suggesting that PTX3 may be a novel biomarker for inflammatory cardiovascular disease8.

Physical form

Supplied as a lyophilized powder containing phosphate buffered saline.

Other Notes

ENSDDYDLMYVNLDNEIDNGLHPTEDPTPCACGQEHSEWDKLFIMLENSQMRERMLLQATDDVLRGELQRLREELGRLAESLARPCAPGAPAEARLTSALDELLQATRDAGRRLARMEGAEAQRPEEAGRALAAVLEELRQTRADLHAVQGWAARSWLPAGCETAILFPMRSKKIFGSVHPVRPMRLESFSACIWVKATDVLNKTILFSYGTKRNPYEIQLYLSYQSIVFVVGGEENKLVAEAMVSLGRWTHLCGTWNSEEGLTSLWVNGELAATTVEMATGHIVPEGGILQIGQEKNGCCVGGGFDETLAFSGRLTGFNIWDSVLSNEEIRETGGAESCHIRGNIVGWGVTEIQPHGGAQYVS

Legal Information

SILu is a trademark of Sigma-Aldrich Co. LLC

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
MSST0003MSST0021MSST0022
SILu&#8482;Lite PTX3&nbsp;Pentraxin-related protein 3 human recombinant, expressed in HEK 293 cells, MS Protein Standard

Sigma-Aldrich

MSST0004

SILu™Lite PTX3 Pentraxin-related protein 3 human

SILu&#8482;Prot PTX3&nbsp;Pentraxin-related protein PTX3 human recombinant, expressed in HEK 293 cells, SIL MS Protein Standard, 13C- and 15N-labeled

Sigma-Aldrich

MSST0003

SILu™Prot PTX3 Pentraxin-related protein PTX3 human

SILu&#8482;Prot CRP C-reactive protein human recombinant, expressed in HEK 293 cells, 13C and 15N-labeled

Sigma-Aldrich

MSST0021

SILu™Prot CRP C-reactive protein human

SILu&#8482;Lite CRP C-reactive Protein human recombinant, expressed in HEK 293 cells, MS Protein Standard

Sigma-Aldrich

MSST0022

SILu™Lite CRP C-reactive Protein human

description

recombinant, expressed in HEK 293 cells, MS Protein Standard

description

recombinant, expressed in HEK 293 cells, SIL MS Protein Standard, 13C- and 15N-labeled

description

recombinant, expressed in HEK 293 cells, 13C and 15N-labeled

description

recombinant, expressed in HEK 293 cells, MS Protein Standard

biological source

human

biological source

human

biological source

human

biological source

human

technique(s)

mass spectrometry (MS): suitable

technique(s)

mass spectrometry (MS): suitable

technique(s)

mass spectrometry (MS): suitable

technique(s)

mass spectrometry (MS): suitable

assay

≥98% (SDS-PAGE)

assay

≥98% (SDS-PAGE)

assay

≥98% (SDS-PAGE)

assay

≥98% (SDS-PAGE)

recombinant

expressed in HEK 293 cells

recombinant

expressed in HEK 293 cells

recombinant

expressed in HEK 293 cells

recombinant

expressed in HEK 293 cells

form

lyophilized powder

form

lyophilized powder

form

liquid

form

liquid

Gene Information

human ... PTX3(5806)

Gene Information

human ... PTX3(5806)

Gene Information

human ... PTX3(5806)

Gene Information

human ... PTX3(5806)

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Questions

Reviews

No rating value

Active Filters