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N0665

NDSB 211

≥98% (TLC)

Synonym(s):

3-[Dimethyl-(2-hydroxyethyl)ammonio]-1-propanesulfonate, Dimethyl(2-hydroxyethyl)(3-sulfopropyl)ammonium hydroxide inner salt, Dimethyl-2-hydroxyethylammoniumpropane sulfonate

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1 g

Available to ship TODAY

$313.00
5 g

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$572.00

About This Item

Empirical Formula (Hill Notation):
C7H17NO4S
CAS Number:
Molecular Weight:
211.28
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12161900
EC Number:
254-176-0
MDL number:

$313.00


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description

zwitterionic

Quality Segment

assay

≥98% (TLC)

form

solid

mol wt

211.28 g/mol

technique(s)

DNA extraction: suitable

color

white

solubility

methanol: 5 mg/mL, clear, colorless

SMILES string

OCC[N+](C)(C)CCCS([O-])(=O)=O

InChI

1S/C7H17NO4S/c1-8(2,5-6-9)4-3-7-13(10,11)12/h9H,3-7H2,1-2H3

InChI key

CNXPCGBLGHKAIL-UHFFFAOYSA-N

General description

Dimethyl-2-hydroxyethylammoniumpropane sulfonate, or NDSB 211, is a nondetergent-sulfobetain. It is zwitterionic over a wide pH range, easily removed by dialysis and shows no significant absorption in the near UV range.

Application

NDSB 211 has been used in a study to assess halophilic protein stabilization by the mild solubilizing agents nondetergent sulfobetaines. It has also been used in a study to investigate an alternative strategy for crystallizing macromolecules.
Non-detergent sulfobetaine is a compound used for non-denaturing protien purification. Increases the extraction yield of membrane, nuclear and cytoskeletal associated proteins. Zwitterionic over a wide pH range, easily removed by dialysis and no significant absorption in the near UV range. Specific applications include microsomal protein extraction, nuclear protein recovery, precipitation reduction in IEF, and membrane-bound protease purification.

Other Notes

This product is non-micelle forming.

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This Item
480001
description

≥98% (TLC)

description

A non-detergent sulfobetaine. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins.

form

solid

form

solid

technique(s)

DNA extraction: suitable

technique(s)

-

assay

≥98% (TLC)

assay

≥95% (TLC)

Quality Level

200

Quality Level

100

mol wt

211.28 g/mol

mol wt

-

description

zwitterionic

description

-


Pictograms

Corrosion

Signal Word

Danger

Hazard Codes

Precautionary Statements

Hazard Classifications

Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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